Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure
Identifieur interne : 006139 ( Main/Exploration ); précédent : 006138; suivant : 006140Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure
Auteurs : Louise V. Wain [Royaume-Uni] ; Germaine C. Verwoert [Pays-Bas] ; Paul F. O Eilly [Royaume-Uni] ; Gang Shi [États-Unis] ; Toby Johnson [Royaume-Uni] ; Andrew D. Johnson [États-Unis] ; Murielle Bochud [Suisse] ; Kenneth M. Rice [États-Unis] ; Peter Henneman [Pays-Bas] ; Albert V. Smith [Islande] ; Georg B. Ehret [États-Unis, Suisse] ; Najaf Amin [Pays-Bas] ; Martin G. Larson [États-Unis] ; Vincent Mooser [États-Unis] ; David Hadley [Royaume-Uni, États-Unis] ; Marcus Dörr [Allemagne] ; Joshua C. Bis [États-Unis] ; Thor Aspelund [Islande] ; T Nu Esko [Estonie] ; A Cecile Jw Janssens [Pays-Bas] ; Jing Hua Zhao [Royaume-Uni] ; Simon Heath [France] ; Maris Laan [Estonie] ; Jingyuan Fu [Pays-Bas] ; Giorgio Pistis [Italie] ; Jian N Luan [Royaume-Uni] ; Pankaj Arora [États-Unis] ; Gavin Lucas [Espagne] ; Nicola Pirastu [Italie] ; Irene Pichler [Allemagne] ; Anne U. Jackson [États-Unis] ; Rebecca J. Webster [Australie] ; Feng Zhang [Royaume-Uni] ; John F. Peden [Royaume-Uni] ; Helena Schmidt [Autriche] ; Toshiko Tanaka [États-Unis] ; Harry Campbell [Royaume-Uni] ; Wilmar Igl [Suède] ; Yuri Milaneschi [États-Unis] ; Jouke-Jan Hotteng [Pays-Bas] ; Veronique Vitart [Royaume-Uni] ; Daniel I. Chasman [États-Unis] ; Stella Trompet [Pays-Bas] ; Jennifer L. Bragg-Gresham [États-Unis] ; Behrooz Z. Alizadeh [Pays-Bas] ; John C. Chambers [Royaume-Uni] ; Xiuqing Guo [États-Unis] ; Terho Lehtim Ki [Finlande] ; Brigitte Kühnel [Allemagne] ; Lorna M. Lopez [Royaume-Uni] ; Ozren Polašek [Croatie] ; Mladen Boban [Croatie] ; Christopher P. Nelson [Royaume-Uni] ; Alanna C. Morrison [États-Unis] ; Vasyl Pihur [États-Unis] ; Santhi K. Ganesh [États-Unis] ; Albert Hofman [Pays-Bas] ; Suman Kundu [Pays-Bas] ; Francesco Us Mattace-Raso [Pays-Bas] ; Fernando Rivadeneira [Pays-Bas] ; Eric Jg Sijbrands [Pays-Bas] ; Andre G. Uitterlinden [Pays-Bas] ; Shih-Jen Hwang [États-Unis] ; Ramachandran S. Vasan [États-Unis] ; Thomas J. Wang [États-Unis] ; Sven Bergmann [Suisse] ; Peter Vollenweider [Suisse] ; Gérard Waeber [Suisse] ; Jaana Laitinen [Finlande] ; Anneli Pouta [Finlande] ; Paavo Zitting [Finlande] ; Wendy L. Mcardle [Royaume-Uni] ; Heyo K. Kroemer [Allemagne] ; Uwe Völker [Allemagne] ; Henry Völzke [Allemagne] ; Nicole L. Glazer [États-Unis] ; Kent D. Taylor [États-Unis] ; Tamara B. Harris [États-Unis] ; Helene Alavere [Estonie] ; Toomas Haller [Estonie] ; Aime Keis [Estonie] ; Mari-Liis Tammesoo [Estonie] ; Yurii Aulchenko [Pays-Bas] ; Inês Barroso [Royaume-Uni] ; Kay-Tee Khaw [Royaume-Uni] ; Pilar Galan [France] ; Serge Hercberg [France] ; Mark Lathrop [France] ; Susana Eyheramendy [Chili] ; Elin Org [Estonie] ; Siim S Ber [Estonie] ; Xiaowen Lu [Pays-Bas] ; Ilja M. Nolte [Pays-Bas] ; Brenda W. Penninx [Pays-Bas] ; Tanguy Corre [Italie] ; Corrado Masciullo [Italie] ; Cinzia Sala [Italie] ; Leif Groop [Suède] ; Benjamin F. Voight [États-Unis] ; Olle Melander [Suède] ; Christopher J. O Onnell ; Veikko Salomaa [Finlande] ; Adamo Pio D Damo [Italie] ; Antonella Fabretto [Italie] ; Flavio Faletra [Italie] ; Sheila Ulivi [Italie] ; M Fabiola Del Greco [Allemagne] ; Maurizio Facheris [Allemagne] ; Francis S. Collins [États-Unis] ; Richard N. Bergman [États-Unis] ; John P. Beilby [Australie] ; Joseph Hung [Australie] ; A William Musk [Australie] ; Massimo Mangino [Royaume-Uni] ; So-Youn Shin [Royaume-Uni] ; Nicole Soranzo [Royaume-Uni] ; Hugh Watkins [Royaume-Uni] ; Anuj Goel [Royaume-Uni] ; Anders Hamsten [Suède] ; Pierre Gider [Autriche] ; Marisa Loitfelder [Autriche] ; Marion Zeginigg [Autriche] ; Dena Hernandez [États-Unis] ; Samer S. Najjar [États-Unis] ; Pau Navarro [Royaume-Uni] ; Sarah H. Wild [Royaume-Uni] ; Anna Maria Corsi [Italie] ; Andrew Singleton [États-Unis] ; Eco Jc De Geus [Pays-Bas] ; Gonneke Willemsen [Pays-Bas] ; Alex N. Parker [États-Unis] ; Lynda M. Rose [États-Unis] ; Brendan Buckley [Irlande (pays)] ; David Stott [Royaume-Uni] ; Marco Orru [Italie] ; Manuela Uda [Italie] ; Melanie M. Van Der Klauw [Pays-Bas] ; Weihua Zhang [Royaume-Uni] ; Xinzhong Li [Royaume-Uni] ; James Scott [Royaume-Uni] ; Yii-Der Ida Chen [États-Unis] ; Gregory L. Burke [États-Unis] ; Mika K Hönen [Finlande] ; Jorma Viikari [Finlande] ; Angela Döring [Allemagne] ; Thomas Meitinger [Allemagne] ; Gail Davies [Royaume-Uni] ; John M. Starr [Royaume-Uni] ; Valur Emilsson [Islande] ; Andrew Plump [États-Unis] ; Jan H. Lindeman [Pays-Bas] ; Peter Ac Hoen [Pays-Bas] ; Inke R. König [Allemagne] ; Janine F. Felix [Pays-Bas, Allemagne] ; Robert Clarke [Royaume-Uni] ; Jemma C. Hopewell [Royaume-Uni] ; Halit Ongen [Royaume-Uni] ; Monique Breteler [Pays-Bas] ; Stéphanie Debette [États-Unis] ; Anita L. Destefano [États-Unis] ; Myriam Fornage [États-Unis] ; Gary F. Mitchell [États-Unis] ; Nicholas L. Smith [États-Unis] ; Hilma Holm [Islande] ; Kari Stefansson [Islande] ; Gudmar Thorleifsson [Islande] ; Unnur Thorsteinsdottir [Islande] ; Nilesh J. Samani [Royaume-Uni] ; Michael Preuss [Allemagne] ; Igor Rudan [Royaume-Uni, Croatie] ; Caroline Hayward [Royaume-Uni] ; Ian J. Deary [Royaume-Uni] ; H-Erich Wichmann [Allemagne] ; Olli T. Raitakari [Finlande] ; Walter Palmas [États-Unis] ; Jaspal S. Kooner [Royaume-Uni] ; Ronald P. Stolk [Pays-Bas] ; J Wouter Jukema [Pays-Bas] ; Alan F. Wright [Royaume-Uni] ; Dorret I. Boomsma [Pays-Bas] ; Stefania Bandinelli [Italie] ; Ulf B. Gyllensten [Suède] ; James F. Wilson [Royaume-Uni] ; Luigi Ferrucci [États-Unis] ; Reinhold Schmidt [Autriche] ; Martin Farrall [Royaume-Uni] ; Tim D. Spector [Royaume-Uni] ; Lyle J. Palmer [Australie, Canada] ; Jaakko Tuomilehto [Finlande] ; Arne Pfeufer [Allemagne] ; Paolo Gasparini [Italie] ; David Siscovick [États-Unis] ; David Altshuler [États-Unis] ; Ruth Jf Loos [Royaume-Uni] ; Daniela Toniolo [Italie] ; Harold Snieder [Pays-Bas] ; Christian Gieger [Allemagne] ; Pierre Meneton [France] ; Nicholas J. Wareham [Royaume-Uni] ; Ben A. Oostra [Pays-Bas] ; Andres Metspalu [Estonie] ; Lenore Launer [États-Unis] ; Rainer Rettig [Allemagne] ; David P. Strachan [Royaume-Uni] ; Jacques S. Beckmann [Suisse] ; Jacqueline Cm Witteman [Pays-Bas] ; Jeanette Erdmann [Allemagne] ; Ko Willems Van Dijk [Pays-Bas] ; Eric Boerwinkle [États-Unis] ; Michael Boehnke [États-Unis] ; Paul M. Ridker [États-Unis, Finlande] ; Marjo-Riitta Jarvelin [Royaume-Uni, Finlande] ; Aravinda Chakravarti [États-Unis] ; Goncalo R. Abecasis [États-Unis] ; Vilmundur Gudnason [Islande] ; Christopher Newton-Cheh [États-Unis] ; Daniel Levy [États-Unis] ; Patricia B. Munroe [Royaume-Uni] ; Bruce M. Psaty [États-Unis] ; Mark J. Caulfield [Royaume-Uni] ; Dabeeru C. Rao [États-Unis] ; Martin D. Tobin [Royaume-Uni] ; Paul Elliott [Royaume-Uni] ; Cornelia M. Van Duijn [Pays-Bas]Source :
- Nature genetics [ 1061-4036 ] ; 2011.
Abstract
Numerous genetic loci influence systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Europeans
Url:
DOI: 10.1038/ng.922
PubMed: 21909110
PubMed Central: 3445021
Affiliations:
- Allemagne, Australie, Autriche, Canada, Chili, Croatie, Espagne, Estonie, Finlande, France, Irlande (pays), Islande, Italie, Pays-Bas, Royaume-Uni, Suisse, Suède, États-Unis
- Angleterre, Angleterre de l'Est, Bade-Wurtemberg, Bavière, Californie, Canton de Vaud, Caroline du Nord, Catalogne, District de Columbia, District de Haute-Bavière, District de Karlsruhe, East Middle Sweden, Finlande occidentale, Floride, Grand Londres, Groningue (province), Hollande-Méridionale, Hollande-Septentrionale, Maryland, Massachusetts, Michigan, Missouri (État), New Jersey, Oxfordshire, Pennsylvanie, Svealand, Texas, Utrecht (province), Uusimaa, Washington (État), Écosse, État de New York, Île-de-France
- Amsterdam, Barcelone, Bobigny, Cambridge, Glasgow, Groningue, Groningue (ville), Heidelberg, Helsinki, Lausanne, Leyde, Londres, Los Angeles, Munich, New York, Oxford, Paris, Rotterdam, Saint-Louis (Missouri), Seattle, Stockholm, Tampa, Turku, Uppsala, Utrecht, Washington (district de Columbia), Édimbourg, Évry (Essonne)
- Université Columbia, Université Louis-et-Maximilien de Munich, Université Paris 13, Université Washington de Saint-Louis, Université d'Helsinki, Université d'Oxford, Université d'Uppsala, Université d'Édimbourg, Université de Californie du Sud, Université de Cambridge, Université de Floride du Sud, Université de Glasgow, Université de Groningue, Université de Lausanne, Université de Londres, Université de Washington, Université technique de Munich
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Le document en format XML
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Bis</name><affiliation wicri:level="4"><nlm:aff id="A26">Cardiovascular Health Research Unit, Division of Internal Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, Division of Internal Medicine, Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Aspelund, Thor" sort="Aspelund, Thor" uniqKey="Aspelund T" first="Thor" last="Aspelund">Thor Aspelund</name><affiliation wicri:level="1"><nlm:aff id="A15">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A16">University of Iceland, Reykajvik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>University of Iceland, Reykajvik</wicri:regionArea><wicri:noRegion>Reykajvik</wicri:noRegion></affiliation></author><author><name sortKey="Esko, T Nu" sort="Esko, T Nu" uniqKey="Esko T" first="T Nu" last="Esko">T Nu Esko</name><affiliation wicri:level="1"><nlm:aff id="A27">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A28">Estonian Biocenter, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Biocenter, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A29">Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Institute of Molecular and Cell Biology, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Janssens, A Cecile Jw" sort="Janssens, A Cecile Jw" uniqKey="Janssens A" first="A Cecile Jw" last="Janssens">A Cecile Jw Janssens</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Zhao, Jing Hua" sort="Zhao, Jing Hua" uniqKey="Zhao J" first="Jing Hua" last="Zhao">Jing Hua Zhao</name><affiliation wicri:level="1"><nlm:aff id="A30">MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Heath, Simon" sort="Heath, Simon" uniqKey="Heath S" first="Simon" last="Heath">Simon Heath</name><affiliation wicri:level="3"><nlm:aff id="A31">Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Évry (Essonne)</settlement></placeName></affiliation></author><author><name sortKey="Laan, Maris" sort="Laan, Maris" uniqKey="Laan M" first="Maris" last="Laan">Maris Laan</name><affiliation wicri:level="1"><nlm:aff id="A29">Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Institute of Molecular and Cell Biology, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Fu, Jingyuan" sort="Fu, Jingyuan" uniqKey="Fu J" first="Jingyuan" last="Fu">Jingyuan Fu</name><affiliation wicri:level="3"><nlm:aff id="A32">Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A33">Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Pistis, Giorgio" sort="Pistis, Giorgio" uniqKey="Pistis G" first="Giorgio" last="Pistis">Giorgio Pistis</name><affiliation wicri:level="1"><nlm:aff id="A34">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Luan, Jian N" sort="Luan, Jian N" uniqKey="Luan J" first="Jian N" last="Luan">Jian N Luan</name><affiliation wicri:level="1"><nlm:aff id="A30">MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Arora, Pankaj" sort="Arora, Pankaj" uniqKey="Arora P" first="Pankaj" last="Arora">Pankaj Arora</name><affiliation wicri:level="2"><nlm:aff id="A35">Center for Human Genetic Research, Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Human Genetic Research, Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Lucas, Gavin" sort="Lucas, Gavin" uniqKey="Lucas G" first="Gavin" last="Lucas">Gavin Lucas</name><affiliation wicri:level="3"><nlm:aff id="A36">Cardiovascular Epidemiology and Genetics, Institut Municipal d’Investigacio Medica, Barcelona Biomedical Research Park, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Cardiovascular Epidemiology and Genetics, Institut Municipal d’Investigacio Medica, Barcelona Biomedical Research Park, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Pirastu, Nicola" sort="Pirastu, Nicola" uniqKey="Pirastu N" first="Nicola" last="Pirastu">Nicola Pirastu</name><affiliation wicri:level="1"><nlm:aff id="A37">Medical Genetics IRCCS Burlo Garofolo/Università degli Studi di Trieste, Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Medical Genetics IRCCS Burlo Garofolo/Università degli Studi di Trieste, Trieste</wicri:regionArea><wicri:noRegion>Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Pichler, Irene" sort="Pichler, Irene" uniqKey="Pichler I" first="Irene" last="Pichler">Irene Pichler</name><affiliation wicri:level="1"><nlm:aff id="A38">Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy. Affiliated Institute of the University of Lübeck, Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy. Affiliated Institute of the University of Lübeck, Lübeck</wicri:regionArea><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion></affiliation></author><author><name sortKey="Jackson, Anne U" sort="Jackson, Anne U" uniqKey="Jackson A" first="Anne U" last="Jackson">Anne U. Jackson</name><affiliation wicri:level="2"><nlm:aff id="A39">Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Webster, Rebecca J" sort="Webster, Rebecca J" uniqKey="Webster R" first="Rebecca J" last="Webster">Rebecca J. Webster</name><affiliation wicri:level="1"><nlm:aff id="A40">Centre for Genetic Epidemiology and Biostatistics, University of Western Australia, Crawley, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Genetic Epidemiology and Biostatistics, University of Western Australia, Crawley, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Feng" sort="Zhang, Feng" uniqKey="Zhang F" first="Feng" last="Zhang">Feng Zhang</name><affiliation wicri:level="3"><nlm:aff id="A41">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Peden, John F" sort="Peden, John F" uniqKey="Peden J" first="John F" last="Peden">John F. Peden</name><affiliation wicri:level="4"><nlm:aff id="A42">Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A43">Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Schmidt, Helena" sort="Schmidt, Helena" uniqKey="Schmidt H" first="Helena" last="Schmidt">Helena Schmidt</name><affiliation wicri:level="1"><nlm:aff id="A44">Institute of Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria</nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea>Institute of Molecular Biology and Biochemistry, Medical University Graz, Graz</wicri:regionArea><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name><affiliation wicri:level="2"><nlm:aff id="A45">Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Clinical Research Branch, National Institute on Aging, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation wicri:level="4"><nlm:aff id="A46">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Igl, Wilmar" sort="Igl, Wilmar" uniqKey="Igl W" first="Wilmar" last="Igl">Wilmar Igl</name><affiliation wicri:level="4"><nlm:aff id="A47">Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Milaneschi, Yuri" sort="Milaneschi, Yuri" uniqKey="Milaneschi Y" first="Yuri" last="Milaneschi">Yuri Milaneschi</name><affiliation wicri:level="2"><nlm:aff id="A45">Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Clinical Research Branch, National Institute on Aging, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Hotteng, Jouke Jan" sort="Hotteng, Jouke Jan" uniqKey="Hotteng J" first="Jouke-Jan" last="Hotteng">Jouke-Jan Hotteng</name><affiliation wicri:level="3"><nlm:aff id="A48">NCA institute, Department of Biological Psychology, VU University, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>NCA institute, Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Vitart, Veronique" sort="Vitart, Veronique" uniqKey="Vitart V" first="Veronique" last="Vitart">Veronique Vitart</name><affiliation wicri:level="3"><nlm:aff id="A49">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Chasman, Daniel I" sort="Chasman, Daniel I" uniqKey="Chasman D" first="Daniel I" last="Chasman">Daniel I. Chasman</name><affiliation wicri:level="2"><nlm:aff id="A50">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A51">Harvard Medical School, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Trompet, Stella" sort="Trompet, Stella" uniqKey="Trompet S" first="Stella" last="Trompet">Stella Trompet</name><affiliation wicri:level="3"><nlm:aff id="A52">Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Cardiology, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A53">Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Bragg Gresham, Jennifer L" sort="Bragg Gresham, Jennifer L" uniqKey="Bragg Gresham J" first="Jennifer L" last="Bragg-Gresham">Jennifer L. Bragg-Gresham</name><affiliation wicri:level="2"><nlm:aff id="A39">Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Alizadeh, Behrooz Z" sort="Alizadeh, Behrooz Z" uniqKey="Alizadeh B" first="Behrooz Z" last="Alizadeh">Behrooz Z. Alizadeh</name><affiliation wicri:level="3"><nlm:aff id="A32">Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Chambers, John C" sort="Chambers, John C" uniqKey="Chambers J" first="John C" last="Chambers">John C. Chambers</name><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A54">Ealing Hospital NHS Trust, Middlesex, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ealing Hospital NHS Trust, Middlesex</wicri:regionArea><wicri:noRegion>Middlesex</wicri:noRegion></affiliation></author><author><name sortKey="Guo, Xiuqing" sort="Guo, Xiuqing" uniqKey="Guo X" first="Xiuqing" last="Guo">Xiuqing Guo</name><affiliation wicri:level="2"><nlm:aff id="A55">Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Lehtim Ki, Terho" sort="Lehtim Ki, Terho" uniqKey="Lehtim Ki T" first="Terho" last="Lehtim Ki">Terho Lehtim Ki</name><affiliation wicri:level="1"><nlm:aff id="A56">Department of Clinical Chemistry, University of Tampere and Tampere University Hospital, Tampere, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Chemistry, University of Tampere and Tampere University Hospital, Tampere</wicri:regionArea><wicri:noRegion>Tampere</wicri:noRegion></affiliation></author><author><name sortKey="Kuhnel, Brigitte" sort="Kuhnel, Brigitte" uniqKey="Kuhnel B" first="Brigitte" last="Kühnel">Brigitte Kühnel</name><affiliation wicri:level="1"><nlm:aff id="A57">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Lopez, Lorna M" sort="Lopez, Lorna M" uniqKey="Lopez L" first="Lorna M" last="Lopez">Lorna M. Lopez</name><affiliation wicri:level="4"><nlm:aff id="A58">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A59">Department of Psychology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Psychology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polašek">Ozren Polašek</name><affiliation wicri:level="1"><nlm:aff id="A60">Department of Public Health, Medical School, University of Split, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Department of Public Health, Medical School, University of Split, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Boban, Mladen" sort="Boban, Mladen" uniqKey="Boban M" first="Mladen" last="Boban">Mladen Boban</name><affiliation wicri:level="1"><nlm:aff id="A61">Department of Pharmacology, Medical School, University of Split, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Department of Pharmacology, Medical School, University of Split, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Nelson, Christopher P" sort="Nelson, Christopher P" uniqKey="Nelson C" first="Christopher P" last="Nelson">Christopher P. Nelson</name><affiliation wicri:level="1"><nlm:aff id="A62">Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation></author><author><name sortKey="Morrison, Alanna C" sort="Morrison, Alanna C" uniqKey="Morrison A" first="Alanna C" last="Morrison">Alanna C. Morrison</name><affiliation wicri:level="2"><nlm:aff id="A63">Division of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas at Houston Health Science Center, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas at Houston Health Science Center, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Pihur, Vasyl" sort="Pihur, Vasyl" uniqKey="Pihur V" first="Vasyl" last="Pihur">Vasyl Pihur</name><affiliation wicri:level="2"><nlm:aff id="A17">Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Ganesh, Santhi K" sort="Ganesh, Santhi K" uniqKey="Ganesh S" first="Santhi K" last="Ganesh">Santhi K. Ganesh</name><affiliation wicri:level="2"><nlm:aff id="A64">Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical Center, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Kundu, Suman" sort="Kundu, Suman" uniqKey="Kundu S" first="Suman" last="Kundu">Suman Kundu</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Mattace Raso, Francesco Us" sort="Mattace Raso, Francesco Us" uniqKey="Mattace Raso F" first="Francesco Us" last="Mattace-Raso">Francesco Us Mattace-Raso</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A3">Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><affiliation wicri:level="3"><nlm:aff id="A3">Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation><nlm:aff id="A4">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</nlm:aff></affiliation></author><author><name sortKey="Sijbrands, Eric Jg" sort="Sijbrands, Eric Jg" uniqKey="Sijbrands E" first="Eric Jg" last="Sijbrands">Eric Jg Sijbrands</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A3">Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="Andre G" last="Uitterlinden">Andre G. Uitterlinden</name><affiliation wicri:level="3"><nlm:aff id="A3">Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation><nlm:aff id="A4">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</nlm:aff></affiliation></author><author><name sortKey="Hwang, Shih Jen" sort="Hwang, Shih Jen" uniqKey="Hwang S" first="Shih-Jen" last="Hwang">Shih-Jen Hwang</name><affiliation wicri:level="2"><nlm:aff id="A9">Framingham Heart Study, Framingham, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A65">Center for Population Studies, National Heart Lung, and Blood Institute, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Population Studies, National Heart Lung, and Blood Institute, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A10">National Heart, Lung and Blood Institute, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Heart, Lung and Blood Institute, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Vasan, Ramachandran S" sort="Vasan, Ramachandran S" uniqKey="Vasan R" first="Ramachandran S" last="Vasan">Ramachandran S. Vasan</name><affiliation wicri:level="2"><nlm:aff id="A9">Framingham Heart Study, Framingham, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A66">Division of Epidemiology and Prevention, Boston University School of Medicine, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology and Prevention, Boston University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Wang, Thomas J" sort="Wang, Thomas J" uniqKey="Wang T" first="Thomas J" last="Wang">Thomas J. Wang</name><affiliation wicri:level="2"><nlm:aff id="A9">Framingham Heart Study, Framingham, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A67">Division of Cardiology, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cardiology, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Bergmann, Sven" sort="Bergmann, Sven" uniqKey="Bergmann S" first="Sven" last="Bergmann">Sven Bergmann</name><affiliation wicri:level="4"><nlm:aff id="A68">Département de Génétique Médicale, Université de Lausanne, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Département de Génétique Médicale, Université de Lausanne, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region><settlement type="city">Lausanne</settlement></placeName><orgName type="university">Université de Lausanne</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A69">Swiss Institute of Bioinformatics, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Swiss Institute of Bioinformatics, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Vollenweider, Peter" sort="Vollenweider, Peter" uniqKey="Vollenweider P" first="Peter" last="Vollenweider">Peter Vollenweider</name><affiliation wicri:level="3"><nlm:aff id="A70">Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Waeber, Gerard" sort="Waeber, Gerard" uniqKey="Waeber G" first="Gérard" last="Waeber">Gérard Waeber</name><affiliation wicri:level="3"><nlm:aff id="A70">Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Laitinen, Jaana" sort="Laitinen, Jaana" uniqKey="Laitinen J" first="Jaana" last="Laitinen">Jaana Laitinen</name><affiliation wicri:level="1"><nlm:aff id="A71">Finnish Institute of Occupational Health, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Finnish Institute of Occupational Health, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Pouta, Anneli" sort="Pouta, Anneli" uniqKey="Pouta A" first="Anneli" last="Pouta">Anneli Pouta</name><affiliation wicri:level="1"><nlm:aff id="A72">National Institute for Health and Welfare, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Zitting, Paavo" sort="Zitting, Paavo" uniqKey="Zitting P" first="Paavo" last="Zitting">Paavo Zitting</name><affiliation wicri:level="1"><nlm:aff id="A73">Department of Physiatrics, Lapland Central Hospital, Rovaniemi, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Physiatrics, Lapland Central Hospital, Rovaniemi</wicri:regionArea><wicri:noRegion>Rovaniemi</wicri:noRegion></affiliation></author><author><name sortKey="Mcardle, Wendy L" sort="Mcardle, Wendy L" uniqKey="Mcardle W" first="Wendy L" last="Mcardle">Wendy L. Mcardle</name><affiliation wicri:level="1"><nlm:aff id="A74">ALSPAC Laboratory, Department of Social Medicine, University of Bristol, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>ALSPAC Laboratory, Department of Social Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Kroemer, Heyo K" sort="Kroemer, Heyo K" uniqKey="Kroemer H" first="Heyo K" last="Kroemer">Heyo K. Kroemer</name><affiliation wicri:level="1"><nlm:aff id="A75">Institute of Pharmacology, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Pharmacology, Ernst-Moritz-Arndt-University Greifswald, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Volker, Uwe" sort="Volker, Uwe" uniqKey="Volker U" first="Uwe" last="Völker">Uwe Völker</name><affiliation wicri:level="1"><nlm:aff id="A76">Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name><affiliation wicri:level="1"><nlm:aff id="A77">Institute for Community Medicine, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, Ernst-Moritz-Arndt-University Greifswald, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Glazer, Nicole L" sort="Glazer, Nicole L" uniqKey="Glazer N" first="Nicole L" last="Glazer">Nicole L. Glazer</name><affiliation wicri:level="2"><nlm:aff id="A78">Section of Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Section of Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Taylor, Kent D" sort="Taylor, Kent D" uniqKey="Taylor K" first="Kent D" last="Taylor">Kent D. Taylor</name><affiliation wicri:level="2"><nlm:aff id="A55">Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B" last="Harris">Tamara B. Harris</name><affiliation wicri:level="2"><nlm:aff id="A79">National Institute of Aging’s Laboratory for Epidemiology, Demography and Biometry, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute of Aging’s Laboratory for Epidemiology, Demography and Biometry, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Alavere, Helene" sort="Alavere, Helene" uniqKey="Alavere H" first="Helene" last="Alavere">Helene Alavere</name><affiliation wicri:level="1"><nlm:aff id="A27">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Haller, Toomas" sort="Haller, Toomas" uniqKey="Haller T" first="Toomas" last="Haller">Toomas Haller</name><affiliation wicri:level="1"><nlm:aff id="A27">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Keis, Aime" sort="Keis, Aime" uniqKey="Keis A" first="Aime" last="Keis">Aime Keis</name><affiliation wicri:level="1"><nlm:aff id="A27">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Tammesoo, Mari Liis" sort="Tammesoo, Mari Liis" uniqKey="Tammesoo M" first="Mari-Liis" last="Tammesoo">Mari-Liis Tammesoo</name><affiliation wicri:level="1"><nlm:aff id="A27">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Aulchenko, Yurii" sort="Aulchenko, Yurii" uniqKey="Aulchenko Y" first="Yurii" last="Aulchenko">Yurii Aulchenko</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Inês" last="Barroso">Inês Barroso</name><affiliation wicri:level="1"><nlm:aff id="A80">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A81">University of Cambridge Metabolic Research Labs, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University of Cambridge Metabolic Research Labs, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name><affiliation wicri:level="4"><nlm:aff id="A82">Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Galan, Pilar" sort="Galan, Pilar" uniqKey="Galan P" first="Pilar" last="Galan">Pilar Galan</name><affiliation wicri:level="3"><nlm:aff id="A83">U557 Institut National de la Santé et de la Recherche Médicale, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>U557 Institut National de la Santé et de la Recherche Médicale, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A84">U1125 Institut National de la Recherche Agronomique, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>U1125 Institut National de la Recherche Agronomique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A85">Université Paris 13, Bobigny, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Université Paris 13, Bobigny</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Bobigny</settlement><settlement type="city">Paris</settlement></placeName><orgName type="university">Université Paris 13</orgName></affiliation></author><author><name sortKey="Hercberg, Serge" sort="Hercberg, Serge" uniqKey="Hercberg S" first="Serge" last="Hercberg">Serge Hercberg</name><affiliation wicri:level="3"><nlm:aff id="A83">U557 Institut National de la Santé et de la Recherche Médicale, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>U557 Institut National de la Santé et de la Recherche Médicale, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A84">U1125 Institut National de la Recherche Agronomique, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>U1125 Institut National de la Recherche Agronomique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A85">Université Paris 13, Bobigny, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Université Paris 13, Bobigny</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Bobigny</settlement><settlement type="city">Paris</settlement></placeName><orgName type="university">Université Paris 13</orgName></affiliation></author><author><name sortKey="Lathrop, Mark" sort="Lathrop, Mark" uniqKey="Lathrop M" first="Mark" last="Lathrop">Mark Lathrop</name><affiliation wicri:level="3"><nlm:aff id="A31">Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Évry (Essonne)</settlement></placeName></affiliation></author><author><name sortKey="Eyheramendy, Susana" sort="Eyheramendy, Susana" uniqKey="Eyheramendy S" first="Susana" last="Eyheramendy">Susana Eyheramendy</name><affiliation wicri:level="1"><nlm:aff id="A86">Department of Statistics, Pontificia Universidad Catolica de Chile, Santiago, Chile</nlm:aff><country xml:lang="fr">Chili</country><wicri:regionArea>Department of Statistics, Pontificia Universidad Catolica de Chile, Santiago</wicri:regionArea><wicri:noRegion>Santiago</wicri:noRegion></affiliation></author><author><name sortKey="Org, Elin" sort="Org, Elin" uniqKey="Org E" first="Elin" last="Org">Elin Org</name><affiliation wicri:level="1"><nlm:aff id="A29">Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Institute of Molecular and Cell Biology, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="S Ber, Siim" sort="S Ber, Siim" uniqKey="S Ber S" first="Siim" last="S Ber">Siim S Ber</name><affiliation wicri:level="1"><nlm:aff id="A29">Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Institute of Molecular and Cell Biology, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Lu, Xiaowen" sort="Lu, Xiaowen" uniqKey="Lu X" first="Xiaowen" last="Lu">Xiaowen Lu</name><affiliation wicri:level="3"><nlm:aff id="A32">Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Nolte, Ilja M" sort="Nolte, Ilja M" uniqKey="Nolte I" first="Ilja M" last="Nolte">Ilja M. Nolte</name><affiliation wicri:level="3"><nlm:aff id="A32">Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Penninx, Brenda W" sort="Penninx, Brenda W" uniqKey="Penninx B" first="Brenda W" last="Penninx">Brenda W. Penninx</name><affiliation wicri:level="3"><nlm:aff id="A87">Department of Psychiatry/EMGO Institute/Neuroscience Campus, VU University Medical Centre, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Psychiatry/EMGO Institute/Neuroscience Campus, VU University Medical Centre, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A88">Department of Psychiatry, Leiden University Medical Centre, Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Psychiatry, Leiden University Medical Centre, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A89">Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Corre, Tanguy" sort="Corre, Tanguy" uniqKey="Corre T" first="Tanguy" last="Corre">Tanguy Corre</name><affiliation wicri:level="1"><nlm:aff id="A34">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Masciullo, Corrado" sort="Masciullo, Corrado" uniqKey="Masciullo C" first="Corrado" last="Masciullo">Corrado Masciullo</name><affiliation wicri:level="1"><nlm:aff id="A34">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Sala, Cinzia" sort="Sala, Cinzia" uniqKey="Sala C" first="Cinzia" last="Sala">Cinzia Sala</name><affiliation wicri:level="1"><nlm:aff id="A34">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Groop, Leif" sort="Groop, Leif" uniqKey="Groop L" first="Leif" last="Groop">Leif Groop</name><affiliation wicri:level="1"><nlm:aff id="A90">Department of Clinical Sciences, Diabetes and Endocrinology Research Unit, Lund University, University Hospital Malmö, Malmö, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology Research Unit, Lund University, University Hospital Malmö, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Voight, Benjamin F" sort="Voight, Benjamin F" uniqKey="Voight B" first="Benjamin F" last="Voight">Benjamin F. Voight</name><affiliation wicri:level="2"><nlm:aff id="A91">Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Melander, Olle" sort="Melander, Olle" uniqKey="Melander O" first="Olle" last="Melander">Olle Melander</name><affiliation wicri:level="1"><nlm:aff id="A92">Department of Clinical Sciences, Hypertension and Cardiovascular Diseases, University Hospital, Malmö, Lund University, Malmö 20502, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Sciences, Hypertension and Cardiovascular Diseases, University Hospital, Malmö, Lund University, Malmö 20502</wicri:regionArea><wicri:noRegion>Malmö 20502</wicri:noRegion></affiliation></author><author><name sortKey="O Onnell, Christopher J" sort="O Onnell, Christopher J" uniqKey="O Onnell C" first="Christopher J" last="O Onnell">Christopher J. O Onnell</name><affiliation><nlm:aff id="A93">National Heart, Lung and Blood Institute and its Framingham Heart Study, 73 Mount Wayte Ave., Suite</nlm:aff><wicri:noCountry code="subfield">Suite</wicri:noCountry></affiliation></author><author><name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name><affiliation wicri:level="1"><nlm:aff id="A94">Department of Chronic Disease Prevention, THL-National Institute for Health and Welfare, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Chronic Disease Prevention, THL-National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="D Damo, Adamo Pio" sort="D Damo, Adamo Pio" uniqKey="D Damo A" first="Adamo Pio" last="D Damo">Adamo Pio D Damo</name><affiliation wicri:level="1"><nlm:aff id="A37">Medical Genetics IRCCS Burlo Garofolo/Università degli Studi di Trieste, Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Medical Genetics IRCCS Burlo Garofolo/Università degli Studi di Trieste, Trieste</wicri:regionArea><wicri:noRegion>Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Fabretto, Antonella" sort="Fabretto, Antonella" uniqKey="Fabretto A" first="Antonella" last="Fabretto">Antonella Fabretto</name><affiliation wicri:level="1"><nlm:aff id="A95">IRCSS Burlo Garofolo Medical Genetics, Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>IRCSS Burlo Garofolo Medical Genetics, Trieste</wicri:regionArea><wicri:noRegion>Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Faletra, Flavio" sort="Faletra, Flavio" uniqKey="Faletra F" first="Flavio" last="Faletra">Flavio Faletra</name><affiliation wicri:level="1"><nlm:aff id="A95">IRCSS Burlo Garofolo Medical Genetics, Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>IRCSS Burlo Garofolo Medical Genetics, Trieste</wicri:regionArea><wicri:noRegion>Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Ulivi, Sheila" sort="Ulivi, Sheila" uniqKey="Ulivi S" first="Sheila" last="Ulivi">Sheila Ulivi</name><affiliation wicri:level="1"><nlm:aff id="A37">Medical Genetics IRCCS Burlo Garofolo/Università degli Studi di Trieste, Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Medical Genetics IRCCS Burlo Garofolo/Università degli Studi di Trieste, Trieste</wicri:regionArea><wicri:noRegion>Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Del Greco, M Fabiola" sort="Del Greco, M Fabiola" uniqKey="Del Greco M" first="M Fabiola" last="Del Greco">M Fabiola Del Greco</name><affiliation wicri:level="1"><nlm:aff id="A38">Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy. Affiliated Institute of the University of Lübeck, Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy. Affiliated Institute of the University of Lübeck, Lübeck</wicri:regionArea><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion></affiliation></author><author><name sortKey="Facheris, Maurizio" sort="Facheris, Maurizio" uniqKey="Facheris M" first="Maurizio" last="Facheris">Maurizio Facheris</name><affiliation wicri:level="1"><nlm:aff id="A38">Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy. Affiliated Institute of the University of Lübeck, Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy. Affiliated Institute of the University of Lübeck, Lübeck</wicri:regionArea><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion></affiliation></author><author><name sortKey="Collins, Francis S" sort="Collins, Francis S" uniqKey="Collins F" first="Francis S" last="Collins">Francis S. Collins</name><affiliation wicri:level="2"><nlm:aff id="A96">National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Bergman, Richard N" sort="Bergman, Richard N" uniqKey="Bergman R" first="Richard N" last="Bergman">Richard N. Bergman</name><affiliation wicri:level="4"><nlm:aff id="A97">Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Beilby, John P" sort="Beilby, John P" uniqKey="Beilby J" first="John P" last="Beilby">John P. Beilby</name><affiliation wicri:level="1"><nlm:aff id="A98">Pathology and Laboratory Medicine, University of Western Australia, Crawley, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Pathology and Laboratory Medicine, University of Western Australia, Crawley, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A99">Molecular Genetics, PathWest Laboratory Medicine, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Molecular Genetics, PathWest Laboratory Medicine, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A100">Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Hung, Joseph" sort="Hung, Joseph" uniqKey="Hung J" first="Joseph" last="Hung">Joseph Hung</name><affiliation wicri:level="1"><nlm:aff id="A101">School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A100">Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Musk, A William" sort="Musk, A William" uniqKey="Musk A" first="A William" last="Musk">A William Musk</name><affiliation wicri:level="1"><nlm:aff id="A100">Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A102">School of Medicine and Pharmcology, University of Western Australia, Crawley, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Medicine and Pharmcology, University of Western Australia, Crawley, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A103">Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name><affiliation wicri:level="3"><nlm:aff id="A41">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Shin, So Youn" sort="Shin, So Youn" uniqKey="Shin S" first="So-Youn" last="Shin">So-Youn Shin</name><affiliation wicri:level="1"><nlm:aff id="A80">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A41">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Soranzo, Nicole" sort="Soranzo, Nicole" uniqKey="Soranzo N" first="Nicole" last="Soranzo">Nicole Soranzo</name><affiliation wicri:level="1"><nlm:aff id="A80">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A41">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Watkins, Hugh" sort="Watkins, Hugh" uniqKey="Watkins H" first="Hugh" last="Watkins">Hugh Watkins</name><affiliation wicri:level="4"><nlm:aff id="A42">Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A43">Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Goel, Anuj" sort="Goel, Anuj" uniqKey="Goel A" first="Anuj" last="Goel">Anuj Goel</name><affiliation wicri:level="4"><nlm:aff id="A42">Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A43">Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name><affiliation wicri:level="3"><nlm:aff id="A104">Atherosclerosis Research Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Gider, Pierre" sort="Gider, Pierre" uniqKey="Gider P" first="Pierre" last="Gider">Pierre Gider</name><affiliation wicri:level="1"><nlm:aff id="A44">Institute of Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria</nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea>Institute of Molecular Biology and Biochemistry, Medical University Graz, Graz</wicri:regionArea><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Loitfelder, Marisa" sort="Loitfelder, Marisa" uniqKey="Loitfelder M" first="Marisa" last="Loitfelder">Marisa Loitfelder</name><affiliation wicri:level="1"><nlm:aff id="A105">Department of Neurology Section of Special Neurology, Medical University Graz, Graz, Austria</nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology Section of Special Neurology, Medical University Graz, Graz</wicri:regionArea><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Zeginigg, Marion" sort="Zeginigg, Marion" uniqKey="Zeginigg M" first="Marion" last="Zeginigg">Marion Zeginigg</name><affiliation wicri:level="1"><nlm:aff id="A44">Institute of Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria</nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea>Institute of Molecular Biology and Biochemistry, Medical University Graz, Graz</wicri:regionArea><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Hernandez, Dena" sort="Hernandez, Dena" uniqKey="Hernandez D" first="Dena" last="Hernandez">Dena Hernandez</name><affiliation wicri:level="2"><nlm:aff id="A106">National Institute of Aging’s Laboratory of Neurogenetics, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute of Aging’s Laboratory of Neurogenetics, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Najjar, Samer S" sort="Najjar, Samer S" uniqKey="Najjar S" first="Samer S" last="Najjar">Samer S. Najjar</name><affiliation wicri:level="2"><nlm:aff id="A107">Laboratory of Cardiovascular Science, Intramural Research Program, National Institute on Aging, NIH, Baltimore, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Cardiovascular Science, Intramural Research Program, National Institute on Aging, NIH, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A108">Cardiovascular Research Institute, MedStar Health Research Institute, Washington Hospital Center, Washington DC, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Research Institute, MedStar Health Research Institute, Washington Hospital Center, Washington DC</wicri:regionArea><placeName><settlement type="city">Washington (district de Columbia)</settlement><region type="state">District de Columbia</region></placeName></affiliation></author><author><name sortKey="Navarro, Pau" sort="Navarro, Pau" uniqKey="Navarro P" first="Pau" last="Navarro">Pau Navarro</name><affiliation wicri:level="3"><nlm:aff id="A49">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Wild, Sarah H" sort="Wild, Sarah H" uniqKey="Wild S" first="Sarah H" last="Wild">Sarah H. Wild</name><affiliation wicri:level="4"><nlm:aff id="A46">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Corsi, Anna Maria" sort="Corsi, Anna Maria" uniqKey="Corsi A" first="Anna Maria" last="Corsi">Anna Maria Corsi</name><affiliation wicri:level="1"><nlm:aff id="A109">Tuscany Regional Health Agency, Florence, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Tuscany Regional Health Agency, Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation></author><author><name sortKey="Singleton, Andrew" sort="Singleton, Andrew" uniqKey="Singleton A" first="Andrew" last="Singleton">Andrew Singleton</name><affiliation wicri:level="2"><nlm:aff id="A106">National Institute of Aging’s Laboratory of Neurogenetics, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute of Aging’s Laboratory of Neurogenetics, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="De Geus, Eco Jc" sort="De Geus, Eco Jc" uniqKey="De Geus E" first="Eco Jc" last="De Geus">Eco Jc De Geus</name><affiliation wicri:level="3"><nlm:aff id="A110">EMGO+ institute, Department of Biological Psychology, VU University, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>EMGO+ institute, Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Willemsen, Gonneke" sort="Willemsen, Gonneke" uniqKey="Willemsen G" first="Gonneke" last="Willemsen">Gonneke Willemsen</name><affiliation wicri:level="3"><nlm:aff id="A110">EMGO+ institute, Department of Biological Psychology, VU University, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>EMGO+ institute, Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Parker, Alex N" sort="Parker, Alex N" uniqKey="Parker A" first="Alex N" last="Parker">Alex N. Parker</name><affiliation wicri:level="2"><nlm:aff id="A111">Amgen, Cambridge, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Amgen, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Rose, Lynda M" sort="Rose, Lynda M" uniqKey="Rose L" first="Lynda M" last="Rose">Lynda M. Rose</name><affiliation wicri:level="2"><nlm:aff id="A50">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Buckley, Brendan" sort="Buckley, Brendan" uniqKey="Buckley B" first="Brendan" last="Buckley">Brendan Buckley</name><affiliation wicri:level="1"><nlm:aff id="A112">Department of Pharmacology and Therapeutics, University College Cork, Cork, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Pharmacology and Therapeutics, University College Cork, Cork</wicri:regionArea><wicri:noRegion>Cork</wicri:noRegion></affiliation></author><author><name sortKey="Stott, David" sort="Stott, David" uniqKey="Stott D" first="David" last="Stott">David Stott</name><affiliation wicri:level="4"><nlm:aff id="A113">Institute of Cardiovascular and Medical Sciences, School of Medicine, University of Glasgow, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Cardiovascular and Medical Sciences, School of Medicine, University of Glasgow</wicri:regionArea><placeName><settlement type="city">Glasgow</settlement><region type="country">Écosse</region></placeName><orgName type="university">Université de Glasgow</orgName></affiliation></author><author><name sortKey="Orru, Marco" sort="Orru, Marco" uniqKey="Orru M" first="Marco" last="Orru">Marco Orru</name><affiliation wicri:level="1"><nlm:aff id="A114">Istituto di Neurogenetica e Neurofarmacologia, Consiglio Nazionale delle Ricerche, Monserrato, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto di Neurogenetica e Neurofarmacologia, Consiglio Nazionale delle Ricerche, Monserrato</wicri:regionArea><wicri:noRegion>Monserrato</wicri:noRegion></affiliation></author><author><name sortKey="Uda, Manuela" sort="Uda, Manuela" uniqKey="Uda M" first="Manuela" last="Uda">Manuela Uda</name><affiliation wicri:level="1"><nlm:aff id="A114">Istituto di Neurogenetica e Neurofarmacologia, Consiglio Nazionale delle Ricerche, Monserrato, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto di Neurogenetica e Neurofarmacologia, Consiglio Nazionale delle Ricerche, Monserrato</wicri:regionArea><wicri:noRegion>Monserrato</wicri:noRegion></affiliation></author><author><name sortKey="Van Der Klauw, Melanie M" sort="Van Der Klauw, Melanie M" uniqKey="Van Der Klauw M" first="Melanie M" last="Van Der Klauw">Melanie M. Van Der Klauw</name><affiliation wicri:level="4"><nlm:aff id="A115">Department of Endocrinology, University Medical Center Groningen, University of Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Endocrinology, University Medical Center Groningen, University of Groningen</wicri:regionArea><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName><orgName type="university">Université de Groningue</orgName></affiliation></author><author><name sortKey="Zhang, Weihua" sort="Zhang, Weihua" uniqKey="Zhang W" first="Weihua" last="Zhang">Weihua Zhang</name><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A54">Ealing Hospital NHS Trust, Middlesex, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ealing Hospital NHS Trust, Middlesex</wicri:regionArea><wicri:noRegion>Middlesex</wicri:noRegion></affiliation></author><author><name sortKey="Li, Xinzhong" sort="Li, Xinzhong" uniqKey="Li X" first="Xinzhong" last="Li">Xinzhong Li</name><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Scott, James" sort="Scott, James" uniqKey="Scott J" first="James" last="Scott">James Scott</name><affiliation wicri:level="3"><nlm:aff id="A116">National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Chen, Yii Der Ida" sort="Chen, Yii Der Ida" uniqKey="Chen Y" first="Yii-Der Ida" last="Chen">Yii-Der Ida Chen</name><affiliation wicri:level="2"><nlm:aff id="A55">Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Burke, Gregory L" sort="Burke, Gregory L" uniqKey="Burke G" first="Gregory L" last="Burke">Gregory L. Burke</name><affiliation wicri:level="2"><nlm:aff id="A117">Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="K Honen, Mika" sort="K Honen, Mika" uniqKey="K Honen M" first="Mika" last="K Hönen">Mika K Hönen</name><affiliation wicri:level="1"><nlm:aff id="A118">Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere</wicri:regionArea><wicri:noRegion>Tampere</wicri:noRegion></affiliation></author><author><name sortKey="Viikari, Jorma" sort="Viikari, Jorma" uniqKey="Viikari J" first="Jorma" last="Viikari">Jorma Viikari</name><affiliation wicri:level="3"><nlm:aff id="A119">Department of Medicine, University of Turku and Turku University Hospital, Turku, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, University of Turku and Turku University Hospital, Turku</wicri:regionArea><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region></placeName></affiliation></author><author><name sortKey="Doring, Angela" sort="Doring, Angela" uniqKey="Doring A" first="Angela" last="Döring">Angela Döring</name><affiliation wicri:level="1"><nlm:aff id="A120">Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A121">Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Meitinger, Thomas" sort="Meitinger, Thomas" uniqKey="Meitinger T" first="Thomas" last="Meitinger">Thomas Meitinger</name><affiliation wicri:level="1"><nlm:aff id="A122">Institute of Human Genetics, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A123">Institute of Human Genetics, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Davies, Gail" sort="Davies, Gail" uniqKey="Davies G" first="Gail" last="Davies">Gail Davies</name><affiliation wicri:level="4"><nlm:aff id="A59">Department of Psychology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Psychology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Starr, John M" sort="Starr, John M" uniqKey="Starr J" first="John M" last="Starr">John M. Starr</name><affiliation wicri:level="4"><nlm:aff id="A58">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A124">Geriatric Medicine Unit, The University of Edinburgh, Royal Victoria, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Geriatric Medicine Unit, The University of Edinburgh, Royal Victoria, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Emilsson, Valur" sort="Emilsson, Valur" uniqKey="Emilsson V" first="Valur" last="Emilsson">Valur Emilsson</name><affiliation wicri:level="1"><nlm:aff id="A15">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation></author><author><name sortKey="Plump, Andrew" sort="Plump, Andrew" uniqKey="Plump A" first="Andrew" last="Plump">Andrew Plump</name><affiliation wicri:level="2"><nlm:aff id="A125">Cardiovascular Disease Franchise, Merck Research Laboratory, Rahway, New Jersey, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Disease Franchise, Merck Research Laboratory, Rahway, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Lindeman, Jan H" sort="Lindeman, Jan H" uniqKey="Lindeman J" first="Jan H" last="Lindeman">Jan H. Lindeman</name><affiliation wicri:level="3"><nlm:aff id="A126">Department of Vascular Surgery, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Vascular Surgery, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey=" Hoen, Peter Ac" sort=" Hoen, Peter Ac" uniqKey=" Hoen P" first="Peter Ac" last=" Hoen">Peter Ac Hoen</name><affiliation wicri:level="3"><nlm:aff id="A127">Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Human Genetics, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A128">Leiden Genome Technology Center, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Leiden Genome Technology Center, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Konig, Inke R" sort="Konig, Inke R" uniqKey="Konig I" first="Inke R" last="König">Inke R. König</name><affiliation wicri:level="1"><nlm:aff id="A129">Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Lübeck</wicri:regionArea><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion></affiliation></author><author><name sortKey="Felix, Janine F" sort="Felix, Janine F" uniqKey="Felix J" first="Janine F" last="Felix">Janine F. Felix</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation><nlm:aff id="A4">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</nlm:aff></affiliation><affiliation wicri:level="3"><nlm:aff id="A130">German Cancer Research Center, Division of Clinical Epidemiology and Aging Research, Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Cancer Research Center, Division of Clinical Epidemiology and Aging Research, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Clarke, Robert" sort="Clarke, Robert" uniqKey="Clarke R" first="Robert" last="Clarke">Robert Clarke</name><affiliation wicri:level="4"><nlm:aff id="A131">Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Hopewell, Jemma C" sort="Hopewell, Jemma C" uniqKey="Hopewell J" first="Jemma C" last="Hopewell">Jemma C. Hopewell</name><affiliation wicri:level="4"><nlm:aff id="A131">Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Ongen, Halit" sort="Ongen, Halit" uniqKey="Ongen H" first="Halit" last="Ongen">Halit Ongen</name><affiliation wicri:level="4"><nlm:aff id="A42">Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Breteler, Monique" sort="Breteler, Monique" uniqKey="Breteler M" first="Monique" last="Breteler">Monique Breteler</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Debette, Stephanie" sort="Debette, Stephanie" uniqKey="Debette S" first="Stéphanie" last="Debette">Stéphanie Debette</name><affiliation wicri:level="2"><nlm:aff id="A132">Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Boston University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Destefano, Anita L" sort="Destefano, Anita L" uniqKey="Destefano A" first="Anita L" last="Destefano">Anita L. Destefano</name><affiliation wicri:level="2"><nlm:aff id="A133">Boston University School of Public Health, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Fornage, Myriam" sort="Fornage, Myriam" uniqKey="Fornage M" first="Myriam" last="Fornage">Myriam Fornage</name><affiliation wicri:level="2"><nlm:aff id="A134">Brown Foundation Institute of Molecular Medicine and Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Brown Foundation Institute of Molecular Medicine and Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Mitchell, Gary F" sort="Mitchell, Gary F" uniqKey="Mitchell G" first="Gary F" last="Mitchell">Gary F. Mitchell</name><affiliation wicri:level="2"><nlm:aff id="A135">Cardiovascular Engineering, Inc., Norwood, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Engineering, Inc., Norwood, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Smith, Nicholas L" sort="Smith, Nicholas L" uniqKey="Smith N" first="Nicholas L" last="Smith">Nicholas L. Smith</name><affiliation wicri:level="4"><nlm:aff id="A136">Department of Epidemiology, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="2"><nlm:aff id="A137">Seattle Epidemiologic Research and Information, Center of the Department of Veterans Affairs Office of Research and Development, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Epidemiologic Research and Information, Center of the Department of Veterans Affairs Office of Research and Development, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A138">Group Health Research Institute, Group Health Cooperative, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Group Health Research Institute, Group Health Cooperative, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Holm, Hilma" sort="Holm, Hilma" uniqKey="Holm H" first="Hilma" last="Holm">Hilma Holm</name><affiliation wicri:level="1"><nlm:aff id="A139">deCODE genetics Inc, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE genetics Inc, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Stefansson, Kari" sort="Stefansson, Kari" uniqKey="Stefansson K" first="Kari" last="Stefansson">Kari Stefansson</name><affiliation wicri:level="1"><nlm:aff id="A139">deCODE genetics Inc, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE genetics Inc, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A140">Faculty of Medicine, University of Iceland, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Thorleifsson, Gudmar" sort="Thorleifsson, Gudmar" uniqKey="Thorleifsson G" first="Gudmar" last="Thorleifsson">Gudmar Thorleifsson</name><affiliation wicri:level="1"><nlm:aff id="A139">deCODE genetics Inc, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE genetics Inc, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Thorsteinsdottir, Unnur" sort="Thorsteinsdottir, Unnur" uniqKey="Thorsteinsdottir U" first="Unnur" last="Thorsteinsdottir">Unnur Thorsteinsdottir</name><affiliation wicri:level="1"><nlm:aff id="A139">deCODE genetics Inc, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE genetics Inc, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A140">Faculty of Medicine, University of Iceland, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Samani, Nilesh J" sort="Samani, Nilesh J" uniqKey="Samani N" first="Nilesh J" last="Samani">Nilesh J. Samani</name><affiliation wicri:level="1"><nlm:aff id="A62">Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A141">Leicester NIHR Biomedical Research Unit in Cardiovascular Disease, Glenfield Hospital, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Leicester NIHR Biomedical Research Unit in Cardiovascular Disease, Glenfield Hospital, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation></author><author><name sortKey="Preuss, Michael" sort="Preuss, Michael" uniqKey="Preuss M" first="Michael" last="Preuss">Michael Preuss</name><affiliation wicri:level="1"><nlm:aff id="A142">Medizinische Klinik II, Universität zu Lübeck, Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Medizinische Klinik II, Universität zu Lübeck, Lübeck</wicri:regionArea><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A129">Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Lübeck</wicri:regionArea><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation wicri:level="4"><nlm:aff id="A46">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A143">Croatian Centre for Global Health, University of Split Medical School, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Croatian Centre for Global Health, University of Split Medical School, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><affiliation wicri:level="3"><nlm:aff id="A49">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Deary, Ian J" sort="Deary, Ian J" uniqKey="Deary I" first="Ian J" last="Deary">Ian J. Deary</name><affiliation wicri:level="4"><nlm:aff id="A58">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A59">Department of Psychology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Psychology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Wichmann, H Erich" sort="Wichmann, H Erich" uniqKey="Wichmann H" first="H-Erich" last="Wichmann">H-Erich Wichmann</name><affiliation wicri:level="1"><nlm:aff id="A120">Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A144">Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität and Klinikum Grosshadern, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität and Klinikum Grosshadern, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Raitakari, Olli T" sort="Raitakari, Olli T" uniqKey="Raitakari O" first="Olli T" last="Raitakari">Olli T. Raitakari</name><affiliation wicri:level="3"><nlm:aff id="A145">Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku and the Department of Clinical Physiology, Turku University Hospital, Turku, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku and the Department of Clinical Physiology, Turku University Hospital, Turku</wicri:regionArea><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region></placeName></affiliation></author><author><name sortKey="Palmas, Walter" sort="Palmas, Walter" uniqKey="Palmas W" first="Walter" last="Palmas">Walter Palmas</name><affiliation wicri:level="4"><nlm:aff id="A146">Columbia University, New York, New York, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Columbia University, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Kooner, Jaspal S" sort="Kooner, Jaspal S" uniqKey="Kooner J" first="Jaspal S" last="Kooner">Jaspal S. Kooner</name><affiliation wicri:level="3"><nlm:aff id="A116">National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A54">Ealing Hospital NHS Trust, Middlesex, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ealing Hospital NHS Trust, Middlesex</wicri:regionArea><wicri:noRegion>Middlesex</wicri:noRegion></affiliation></author><author><name sortKey="Stolk, Ronald P" sort="Stolk, Ronald P" uniqKey="Stolk R" first="Ronald P" last="Stolk">Ronald P. Stolk</name><affiliation wicri:level="4"><nlm:aff id="A147">Department of Epidemiology, University Medical Center Groningen, University of Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, University Medical Center Groningen, University of Groningen</wicri:regionArea><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName><orgName type="university">Université de Groningue</orgName></affiliation></author><author><name sortKey="Jukema, J Wouter" sort="Jukema, J Wouter" uniqKey="Jukema J" first="J Wouter" last="Jukema">J Wouter Jukema</name><affiliation wicri:level="3"><nlm:aff id="A52">Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Cardiology, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A148">Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Durrer Center for Cardiogenetic Research, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A149">Interuniversity Cardiology Institute of the Netherlands, Utrecht, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Interuniversity Cardiology Institute of the Netherlands, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F" last="Wright">Alan F. Wright</name><affiliation wicri:level="3"><nlm:aff id="A49">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I" last="Boomsma">Dorret I. Boomsma</name><affiliation wicri:level="3"><nlm:aff id="A110">EMGO+ institute, Department of Biological Psychology, VU University, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>EMGO+ institute, Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Bandinelli, Stefania" sort="Bandinelli, Stefania" uniqKey="Bandinelli S" first="Stefania" last="Bandinelli">Stefania Bandinelli</name><affiliation wicri:level="1"><nlm:aff id="A150">Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation></author><author><name sortKey="Gyllensten, Ulf B" sort="Gyllensten, Ulf B" uniqKey="Gyllensten U" first="Ulf B" last="Gyllensten">Ulf B. Gyllensten</name><affiliation wicri:level="4"><nlm:aff id="A47">Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><affiliation wicri:level="4"><nlm:aff id="A46">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name><affiliation wicri:level="2"><nlm:aff id="A45">Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Clinical Research Branch, National Institute on Aging, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Schmidt, Reinhold" sort="Schmidt, Reinhold" uniqKey="Schmidt R" first="Reinhold" last="Schmidt">Reinhold Schmidt</name><affiliation wicri:level="1"><nlm:aff id="A105">Department of Neurology Section of Special Neurology, Medical University Graz, Graz, Austria</nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology Section of Special Neurology, Medical University Graz, Graz</wicri:regionArea><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Farrall, Martin" sort="Farrall, Martin" uniqKey="Farrall M" first="Martin" last="Farrall">Martin Farrall</name><affiliation wicri:level="4"><nlm:aff id="A42">Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A43">Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D" last="Spector">Tim D. Spector</name><affiliation wicri:level="3"><nlm:aff id="A41">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Palmer, Lyle J" sort="Palmer, Lyle J" uniqKey="Palmer L" first="Lyle J" last="Palmer">Lyle J. Palmer</name><affiliation wicri:level="1"><nlm:aff id="A40">Centre for Genetic Epidemiology and Biostatistics, University of Western Australia, Crawley, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Genetic Epidemiology and Biostatistics, University of Western Australia, Crawley, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A100">Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A151">Ontario Institute for Cancer Research, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Ontario Institute for Cancer Research, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A152">Samuel Lunenfeld Research Institute, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Samuel Lunenfeld Research Institute, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name><affiliation wicri:level="1"><nlm:aff id="A153">National Institute for Health and Welfare, Diabetes Prevention Unit, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Diabetes Prevention Unit, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A154">Hjelt Institute, Department of Public Health, University of Helsinki, 00014 Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Hjelt Institute, Department of Public Health, University of Helsinki, 00014 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A155">South Ostrobothnia Central Hospital, Seinajoki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>South Ostrobothnia Central Hospital, Seinajoki</wicri:regionArea><wicri:noRegion>Seinajoki</wicri:noRegion></affiliation></author><author><name sortKey="Pfeufer, Arne" sort="Pfeufer, Arne" uniqKey="Pfeufer A" first="Arne" last="Pfeufer">Arne Pfeufer</name><affiliation wicri:level="1"><nlm:aff id="A38">Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy. Affiliated Institute of the University of Lübeck, Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy. Affiliated Institute of the University of Lübeck, Lübeck</wicri:regionArea><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A156">Institute of Human Genetics, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Klinikum rechts der Isar der Technischen Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A157">Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Gasparini, Paolo" sort="Gasparini, Paolo" uniqKey="Gasparini P" first="Paolo" last="Gasparini">Paolo Gasparini</name><affiliation wicri:level="1"><nlm:aff id="A95">IRCSS Burlo Garofolo Medical Genetics, Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>IRCSS Burlo Garofolo Medical Genetics, Trieste</wicri:regionArea><wicri:noRegion>Trieste</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A37">Medical Genetics IRCCS Burlo Garofolo/Università degli Studi di Trieste, Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Medical Genetics IRCCS Burlo Garofolo/Università degli Studi di Trieste, Trieste</wicri:regionArea><wicri:noRegion>Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Siscovick, David" sort="Siscovick, David" uniqKey="Siscovick D" first="David" last="Siscovick">David Siscovick</name><affiliation wicri:level="4"><nlm:aff id="A158">Department of Medicine, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A136">Department of Epidemiology, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A26">Cardiovascular Health Research Unit, Division of Internal Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, Division of Internal Medicine, Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Altshuler, David" sort="Altshuler, David" uniqKey="Altshuler D" first="David" last="Altshuler">David Altshuler</name><affiliation wicri:level="2"><nlm:aff id="A159">Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A160">Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A91">Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A161">Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Loos, Ruth Jf" sort="Loos, Ruth Jf" uniqKey="Loos R" first="Ruth Jf" last="Loos">Ruth Jf Loos</name><affiliation wicri:level="1"><nlm:aff id="A30">MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Toniolo, Daniela" sort="Toniolo, Daniela" uniqKey="Toniolo D" first="Daniela" last="Toniolo">Daniela Toniolo</name><affiliation wicri:level="1"><nlm:aff id="A34">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A162">Institute of Molecuar Genetics_CNR, Pavia, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Molecuar Genetics_CNR, Pavia</wicri:regionArea><wicri:noRegion>Pavia</wicri:noRegion></affiliation></author><author><name sortKey="Snieder, Harold" sort="Snieder, Harold" uniqKey="Snieder H" first="Harold" last="Snieder">Harold Snieder</name><affiliation wicri:level="3"><nlm:aff id="A32">Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:aff id="A57">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Meneton, Pierre" sort="Meneton, Pierre" uniqKey="Meneton P" first="Pierre" last="Meneton">Pierre Meneton</name><affiliation wicri:level="3"><nlm:aff id="A163">U872 Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>U872 Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J" last="Wareham">Nicholas J. Wareham</name><affiliation wicri:level="1"><nlm:aff id="A30">MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Oostra, Ben A" sort="Oostra, Ben A" uniqKey="Oostra B" first="Ben A" last="Oostra">Ben A. Oostra</name><affiliation wicri:level="3"><nlm:aff id="A164">Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name><affiliation wicri:level="1"><nlm:aff id="A27">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A28">Estonian Biocenter, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Biocenter, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A29">Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Institute of Molecular and Cell Biology, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Launer, Lenore" sort="Launer, Lenore" uniqKey="Launer L" first="Lenore" last="Launer">Lenore Launer</name><affiliation wicri:level="1"><nlm:aff id="A165">National Institute of Aging’s Laboratory for Epidemiology, Demography and Biometry, Bethesda, Marylands, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute of Aging’s Laboratory for Epidemiology, Demography and Biometry, Bethesda, Marylands</wicri:regionArea><wicri:noRegion>Marylands</wicri:noRegion></affiliation></author><author><name sortKey="Rettig, Rainer" sort="Rettig, Rainer" uniqKey="Rettig R" first="Rainer" last="Rettig">Rainer Rettig</name><affiliation wicri:level="1"><nlm:aff id="A166">Institute of Physiology, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Physiology, Ernst-Moritz-Arndt-University Greifswald, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Strachan, David P" sort="Strachan, David P" uniqKey="Strachan D" first="David P" last="Strachan">David P. Strachan</name><affiliation wicri:level="4"><nlm:aff id="A23">Division of Community Health Sciences, St George’s, University of London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Community Health Sciences, St George’s, University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Beckmann, Jacques S" sort="Beckmann, Jacques S" uniqKey="Beckmann J" first="Jacques S" last="Beckmann">Jacques S. Beckmann</name><affiliation wicri:level="4"><nlm:aff id="A68">Département de Génétique Médicale, Université de Lausanne, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Département de Génétique Médicale, Université de Lausanne, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region><settlement type="city">Lausanne</settlement></placeName><orgName type="university">Université de Lausanne</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A167">Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Witteman, Jacqueline Cm" sort="Witteman, Jacqueline Cm" uniqKey="Witteman J" first="Jacqueline Cm" last="Witteman">Jacqueline Cm Witteman</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation><nlm:aff id="A4">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</nlm:aff></affiliation></author><author><name sortKey="Erdmann, Jeanette" sort="Erdmann, Jeanette" uniqKey="Erdmann J" first="Jeanette" last="Erdmann">Jeanette Erdmann</name><affiliation wicri:level="1"><nlm:aff id="A142">Medizinische Klinik II, Universität zu Lübeck, Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Medizinische Klinik II, Universität zu Lübeck, Lübeck</wicri:regionArea><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion></affiliation></author><author><name sortKey="Van Dijk, Ko Willems" sort="Van Dijk, Ko Willems" uniqKey="Van Dijk K" first="Ko Willems" last="Van Dijk">Ko Willems Van Dijk</name><affiliation wicri:level="3"><nlm:aff id="A14">Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Human Genetics, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A168">Department of Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><affiliation wicri:level="2"><nlm:aff id="A169">Human Genetics Center, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genetics Center, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Boehnke, Michael" sort="Boehnke, Michael" uniqKey="Boehnke M" first="Michael" last="Boehnke">Michael Boehnke</name><affiliation wicri:level="2"><nlm:aff id="A39">Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M" last="Ridker">Paul M. Ridker</name><affiliation wicri:level="2"><nlm:aff id="A50">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A170">Division of Cardiology, Brigham and Women’s Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cardiology, Brigham and Women’s Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A51">Harvard Medical School, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A72">National Institute for Health and Welfare, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Jarvelin, Marjo Riitta" sort="Jarvelin, Marjo Riitta" uniqKey="Jarvelin M" first="Marjo-Riitta" last="Jarvelin">Marjo-Riitta Jarvelin</name><affiliation wicri:level="3"><nlm:aff id="A171">Department of Biostatistics and Epidemiology, School of Public Health, Imperial College London, Norfolk Place, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Biostatistics and Epidemiology, School of Public Health, Imperial College London, Norfolk Place, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A172">Institute of Health Sciences, University of Oulu, University of Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute of Health Sciences, University of Oulu, University of Oulu</wicri:regionArea><wicri:noRegion>University of Oulu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A173">Biocenter, University of Oulu, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Biocenter, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Chakravarti, Aravinda" sort="Chakravarti, Aravinda" uniqKey="Chakravarti A" first="Aravinda" last="Chakravarti">Aravinda Chakravarti</name><affiliation wicri:level="2"><nlm:aff id="A17">Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Abecasis, Goncalo R" sort="Abecasis, Goncalo R" uniqKey="Abecasis G" first="Goncalo R" last="Abecasis">Goncalo R. Abecasis</name><affiliation wicri:level="2"><nlm:aff id="A39">Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation wicri:level="1"><nlm:aff id="A15">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A16">University of Iceland, Reykajvik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>University of Iceland, Reykajvik</wicri:regionArea><wicri:noRegion>Reykajvik</wicri:noRegion></affiliation></author><author><name sortKey="Newton Cheh, Christopher" sort="Newton Cheh, Christopher" uniqKey="Newton Cheh C" first="Christopher" last="Newton-Cheh">Christopher Newton-Cheh</name><affiliation wicri:level="2"><nlm:aff id="A35">Center for Human Genetic Research, Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Human Genetic Research, Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A91">Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Levy, Daniel" sort="Levy, Daniel" uniqKey="Levy D" first="Daniel" last="Levy">Daniel Levy</name><affiliation wicri:level="2"><nlm:aff id="A9">Framingham Heart Study, Framingham, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A65">Center for Population Studies, National Heart Lung, and Blood Institute, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Population Studies, National Heart Lung, and Blood Institute, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A10">National Heart, Lung and Blood Institute, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Heart, Lung and Blood Institute, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Munroe, Patricia B" sort="Munroe, Patricia B" uniqKey="Munroe P" first="Patricia B" last="Munroe">Patricia B. Munroe</name><affiliation wicri:level="4"><nlm:aff id="A8">Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M" last="Psaty">Bruce M. Psaty</name><affiliation wicri:level="4"><nlm:aff id="A26">Cardiovascular Health Research Unit, Division of Internal Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, Division of Internal Medicine, Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A136">Department of Epidemiology, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A174">Department of Health Services, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Health Services, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="2"><nlm:aff id="A138">Group Health Research Institute, Group Health Cooperative, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Group Health Research Institute, Group Health Cooperative, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Caulfield, Mark J" sort="Caulfield, Mark J" uniqKey="Caulfield M" first="Mark J" last="Caulfield">Mark J. Caulfield</name><affiliation wicri:level="4"><nlm:aff id="A8">Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Rao, Dabeeru C" sort="Rao, Dabeeru C" uniqKey="Rao D" first="Dabeeru C" last="Rao">Dabeeru C. Rao</name><affiliation wicri:level="4"><nlm:aff id="A6">Division of Biostatistics, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Biostatistics, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">Université Washington de Saint-Louis</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A7">Department of Genetics, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">Université Washington de Saint-Louis</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A175">Department of Psychiatry, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">Université Washington de Saint-Louis</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A176">Department of Mathematics, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Mathematics, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">Université Washington de Saint-Louis</orgName></affiliation></author><author><name sortKey="Tobin, Martin D" sort="Tobin, Martin D" uniqKey="Tobin M" first="Martin D" last="Tobin">Martin D. Tobin</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Health Sciences, University of Leicester, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Health Sciences, University of Leicester, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A2">Department of Genetics, University of Leicester, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genetics, University of Leicester, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation></author><author><name sortKey="Elliott, Paul" sort="Elliott, Paul" uniqKey="Elliott P" first="Paul" last="Elliott">Paul Elliott</name><affiliation wicri:level="3"><nlm:aff id="A177">MRC-HPA Centre for Environment and Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC-HPA Centre for Environment and Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A178">Centre of Medical Systems Biology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Centre of Medical Systems Biology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation><nlm:aff id="A4">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21909110</idno><idno type="pmc">3445021</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445021</idno><idno type="RBID">PMC:3445021</idno><idno type="doi">10.1038/ng.922</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">002E06</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002E06</idno><idno type="wicri:Area/Pmc/Curation">002C56</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002C56</idno><idno type="wicri:Area/Pmc/Checkpoint">002300</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002300</idno><idno type="wicri:Area/Ncbi/Merge">000B65</idno><idno type="wicri:Area/Ncbi/Curation">000B65</idno><idno type="wicri:Area/Ncbi/Checkpoint">000B65</idno><idno type="wicri:doubleKey">1061-4036:2011:Wain L:genome:wide:association</idno><idno type="wicri:Area/Main/Merge">006496</idno><idno type="wicri:Area/Main/Curation">006139</idno><idno type="wicri:Area/Main/Exploration">006139</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure</title><author><name sortKey="Wain, Louise V" sort="Wain, Louise V" uniqKey="Wain L" first="Louise V" last="Wain">Louise V. Wain</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Health Sciences, University of Leicester, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Health Sciences, University of Leicester, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A2">Department of Genetics, University of Leicester, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genetics, University of Leicester, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation></author><author><name sortKey="Verwoert, Germaine C" sort="Verwoert, Germaine C" uniqKey="Verwoert G" first="Germaine C" last="Verwoert">Germaine C. Verwoert</name><affiliation wicri:level="3"><nlm:aff id="A3">Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation><nlm:aff id="A4">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</nlm:aff></affiliation></author><author><name sortKey="O Eilly, Paul F" sort="O Eilly, Paul F" uniqKey="O Eilly P" first="Paul F" last="O Eilly">Paul F. O Eilly</name><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Shi, Gang" sort="Shi, Gang" uniqKey="Shi G" first="Gang" last="Shi">Gang Shi</name><affiliation wicri:level="4"><nlm:aff id="A6">Division of Biostatistics, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Biostatistics, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">Université Washington de Saint-Louis</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A7">Department of Genetics, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">Université Washington de Saint-Louis</orgName></affiliation></author><author><name sortKey="Johnson, Toby" sort="Johnson, Toby" uniqKey="Johnson T" first="Toby" last="Johnson">Toby Johnson</name><affiliation wicri:level="4"><nlm:aff id="A8">Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Johnson, Andrew D" sort="Johnson, Andrew D" uniqKey="Johnson A" first="Andrew D" last="Johnson">Andrew D. Johnson</name><affiliation wicri:level="2"><nlm:aff id="A9">Framingham Heart Study, Framingham, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A10">National Heart, Lung and Blood Institute, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Heart, Lung and Blood Institute, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Bochud, Murielle" sort="Bochud, Murielle" uniqKey="Bochud M" first="Murielle" last="Bochud">Murielle Bochud</name><affiliation wicri:level="1"><nlm:aff id="A11">Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois, 1005 Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois, 1005 Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A12">University of Lausanne, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>University of Lausanne, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Rice, Kenneth M" sort="Rice, Kenneth M" uniqKey="Rice K" first="Kenneth M" last="Rice">Kenneth M. Rice</name><affiliation wicri:level="4"><nlm:aff id="A13">Department of Biostatistics, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Henneman, Peter" sort="Henneman, Peter" uniqKey="Henneman P" first="Peter" last="Henneman">Peter Henneman</name><affiliation wicri:level="3"><nlm:aff id="A14">Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Human Genetics, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V" last="Smith">Albert V. Smith</name><affiliation wicri:level="1"><nlm:aff id="A15">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A16">University of Iceland, Reykajvik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>University of Iceland, Reykajvik</wicri:regionArea><wicri:noRegion>Reykajvik</wicri:noRegion></affiliation></author><author><name sortKey="Ehret, Georg B" sort="Ehret, Georg B" uniqKey="Ehret G" first="Georg B" last="Ehret">Georg B. Ehret</name><affiliation wicri:level="2"><nlm:aff id="A17">Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A18">Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A19">Cardiology, Department of Medicine, Geneva University Hospital, Geneva, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Cardiology, Department of Medicine, Geneva University Hospital, Geneva</wicri:regionArea><wicri:noRegion>Geneva</wicri:noRegion></affiliation></author><author><name sortKey="Amin, Najaf" sort="Amin, Najaf" uniqKey="Amin N" first="Najaf" last="Amin">Najaf Amin</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Larson, Martin G" sort="Larson, Martin G" uniqKey="Larson M" first="Martin G" last="Larson">Martin G. Larson</name><affiliation wicri:level="2"><nlm:aff id="A9">Framingham Heart Study, Framingham, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A21">Department of Mathematics, Boston University, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Mathematics, Boston University, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Mooser, Vincent" sort="Mooser, Vincent" uniqKey="Mooser V" first="Vincent" last="Mooser">Vincent Mooser</name><affiliation wicri:level="2"><nlm:aff id="A22">Genetics Division R&D, GlaxoSmithKline, King of Prussia, Pennsylvania, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Genetics Division R&D, GlaxoSmithKline, King of Prussia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Hadley, David" sort="Hadley, David" uniqKey="Hadley D" first="David" last="Hadley">David Hadley</name><affiliation wicri:level="4"><nlm:aff id="A23">Division of Community Health Sciences, St George’s, University of London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Community Health Sciences, St George’s, University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A24">Pediatric Epidemiology Center, University of South Florida, Tampa, Florida, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Pediatric Epidemiology Center, University of South Florida, Tampa, Florida</wicri:regionArea><placeName><region type="state">Floride</region><settlement type="city">Tampa</settlement></placeName><orgName type="university">Université de Floride du Sud</orgName></affiliation></author><author><name sortKey="Dorr, Marcus" sort="Dorr, Marcus" uniqKey="Dorr M" first="Marcus" last="Dörr">Marcus Dörr</name><affiliation wicri:level="1"><nlm:aff id="A25">Department of Internal Medicine B, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine B, Ernst-Moritz-Arndt-University Greifswald, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Bis, Joshua C" sort="Bis, Joshua C" uniqKey="Bis J" first="Joshua C" last="Bis">Joshua C. Bis</name><affiliation wicri:level="4"><nlm:aff id="A26">Cardiovascular Health Research Unit, Division of Internal Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, Division of Internal Medicine, Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Aspelund, Thor" sort="Aspelund, Thor" uniqKey="Aspelund T" first="Thor" last="Aspelund">Thor Aspelund</name><affiliation wicri:level="1"><nlm:aff id="A15">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A16">University of Iceland, Reykajvik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>University of Iceland, Reykajvik</wicri:regionArea><wicri:noRegion>Reykajvik</wicri:noRegion></affiliation></author><author><name sortKey="Esko, T Nu" sort="Esko, T Nu" uniqKey="Esko T" first="T Nu" last="Esko">T Nu Esko</name><affiliation wicri:level="1"><nlm:aff id="A27">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A28">Estonian Biocenter, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Biocenter, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A29">Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Institute of Molecular and Cell Biology, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Janssens, A Cecile Jw" sort="Janssens, A Cecile Jw" uniqKey="Janssens A" first="A Cecile Jw" last="Janssens">A Cecile Jw Janssens</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Zhao, Jing Hua" sort="Zhao, Jing Hua" uniqKey="Zhao J" first="Jing Hua" last="Zhao">Jing Hua Zhao</name><affiliation wicri:level="1"><nlm:aff id="A30">MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Heath, Simon" sort="Heath, Simon" uniqKey="Heath S" first="Simon" last="Heath">Simon Heath</name><affiliation wicri:level="3"><nlm:aff id="A31">Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Évry (Essonne)</settlement></placeName></affiliation></author><author><name sortKey="Laan, Maris" sort="Laan, Maris" uniqKey="Laan M" first="Maris" last="Laan">Maris Laan</name><affiliation wicri:level="1"><nlm:aff id="A29">Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Institute of Molecular and Cell Biology, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Fu, Jingyuan" sort="Fu, Jingyuan" uniqKey="Fu J" first="Jingyuan" last="Fu">Jingyuan Fu</name><affiliation wicri:level="3"><nlm:aff id="A32">Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A33">Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Pistis, Giorgio" sort="Pistis, Giorgio" uniqKey="Pistis G" first="Giorgio" last="Pistis">Giorgio Pistis</name><affiliation wicri:level="1"><nlm:aff id="A34">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Luan, Jian N" sort="Luan, Jian N" uniqKey="Luan J" first="Jian N" last="Luan">Jian N Luan</name><affiliation wicri:level="1"><nlm:aff id="A30">MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Arora, Pankaj" sort="Arora, Pankaj" uniqKey="Arora P" first="Pankaj" last="Arora">Pankaj Arora</name><affiliation wicri:level="2"><nlm:aff id="A35">Center for Human Genetic Research, Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Human Genetic Research, Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Lucas, Gavin" sort="Lucas, Gavin" uniqKey="Lucas G" first="Gavin" last="Lucas">Gavin Lucas</name><affiliation wicri:level="3"><nlm:aff id="A36">Cardiovascular Epidemiology and Genetics, Institut Municipal d’Investigacio Medica, Barcelona Biomedical Research Park, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Cardiovascular Epidemiology and Genetics, Institut Municipal d’Investigacio Medica, Barcelona Biomedical Research Park, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Pirastu, Nicola" sort="Pirastu, Nicola" uniqKey="Pirastu N" first="Nicola" last="Pirastu">Nicola Pirastu</name><affiliation wicri:level="1"><nlm:aff id="A37">Medical Genetics IRCCS Burlo Garofolo/Università degli Studi di Trieste, Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Medical Genetics IRCCS Burlo Garofolo/Università degli Studi di Trieste, Trieste</wicri:regionArea><wicri:noRegion>Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Pichler, Irene" sort="Pichler, Irene" uniqKey="Pichler I" first="Irene" last="Pichler">Irene Pichler</name><affiliation wicri:level="1"><nlm:aff id="A38">Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy. Affiliated Institute of the University of Lübeck, Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy. Affiliated Institute of the University of Lübeck, Lübeck</wicri:regionArea><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion></affiliation></author><author><name sortKey="Jackson, Anne U" sort="Jackson, Anne U" uniqKey="Jackson A" first="Anne U" last="Jackson">Anne U. Jackson</name><affiliation wicri:level="2"><nlm:aff id="A39">Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Webster, Rebecca J" sort="Webster, Rebecca J" uniqKey="Webster R" first="Rebecca J" last="Webster">Rebecca J. Webster</name><affiliation wicri:level="1"><nlm:aff id="A40">Centre for Genetic Epidemiology and Biostatistics, University of Western Australia, Crawley, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Genetic Epidemiology and Biostatistics, University of Western Australia, Crawley, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Feng" sort="Zhang, Feng" uniqKey="Zhang F" first="Feng" last="Zhang">Feng Zhang</name><affiliation wicri:level="3"><nlm:aff id="A41">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Peden, John F" sort="Peden, John F" uniqKey="Peden J" first="John F" last="Peden">John F. Peden</name><affiliation wicri:level="4"><nlm:aff id="A42">Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A43">Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Schmidt, Helena" sort="Schmidt, Helena" uniqKey="Schmidt H" first="Helena" last="Schmidt">Helena Schmidt</name><affiliation wicri:level="1"><nlm:aff id="A44">Institute of Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria</nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea>Institute of Molecular Biology and Biochemistry, Medical University Graz, Graz</wicri:regionArea><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name><affiliation wicri:level="2"><nlm:aff id="A45">Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Clinical Research Branch, National Institute on Aging, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation wicri:level="4"><nlm:aff id="A46">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Igl, Wilmar" sort="Igl, Wilmar" uniqKey="Igl W" first="Wilmar" last="Igl">Wilmar Igl</name><affiliation wicri:level="4"><nlm:aff id="A47">Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Milaneschi, Yuri" sort="Milaneschi, Yuri" uniqKey="Milaneschi Y" first="Yuri" last="Milaneschi">Yuri Milaneschi</name><affiliation wicri:level="2"><nlm:aff id="A45">Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Clinical Research Branch, National Institute on Aging, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Hotteng, Jouke Jan" sort="Hotteng, Jouke Jan" uniqKey="Hotteng J" first="Jouke-Jan" last="Hotteng">Jouke-Jan Hotteng</name><affiliation wicri:level="3"><nlm:aff id="A48">NCA institute, Department of Biological Psychology, VU University, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>NCA institute, Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Vitart, Veronique" sort="Vitart, Veronique" uniqKey="Vitart V" first="Veronique" last="Vitart">Veronique Vitart</name><affiliation wicri:level="3"><nlm:aff id="A49">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Chasman, Daniel I" sort="Chasman, Daniel I" uniqKey="Chasman D" first="Daniel I" last="Chasman">Daniel I. Chasman</name><affiliation wicri:level="2"><nlm:aff id="A50">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A51">Harvard Medical School, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Trompet, Stella" sort="Trompet, Stella" uniqKey="Trompet S" first="Stella" last="Trompet">Stella Trompet</name><affiliation wicri:level="3"><nlm:aff id="A52">Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Cardiology, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A53">Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Bragg Gresham, Jennifer L" sort="Bragg Gresham, Jennifer L" uniqKey="Bragg Gresham J" first="Jennifer L" last="Bragg-Gresham">Jennifer L. Bragg-Gresham</name><affiliation wicri:level="2"><nlm:aff id="A39">Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Alizadeh, Behrooz Z" sort="Alizadeh, Behrooz Z" uniqKey="Alizadeh B" first="Behrooz Z" last="Alizadeh">Behrooz Z. Alizadeh</name><affiliation wicri:level="3"><nlm:aff id="A32">Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Chambers, John C" sort="Chambers, John C" uniqKey="Chambers J" first="John C" last="Chambers">John C. Chambers</name><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A54">Ealing Hospital NHS Trust, Middlesex, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ealing Hospital NHS Trust, Middlesex</wicri:regionArea><wicri:noRegion>Middlesex</wicri:noRegion></affiliation></author><author><name sortKey="Guo, Xiuqing" sort="Guo, Xiuqing" uniqKey="Guo X" first="Xiuqing" last="Guo">Xiuqing Guo</name><affiliation wicri:level="2"><nlm:aff id="A55">Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Lehtim Ki, Terho" sort="Lehtim Ki, Terho" uniqKey="Lehtim Ki T" first="Terho" last="Lehtim Ki">Terho Lehtim Ki</name><affiliation wicri:level="1"><nlm:aff id="A56">Department of Clinical Chemistry, University of Tampere and Tampere University Hospital, Tampere, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Chemistry, University of Tampere and Tampere University Hospital, Tampere</wicri:regionArea><wicri:noRegion>Tampere</wicri:noRegion></affiliation></author><author><name sortKey="Kuhnel, Brigitte" sort="Kuhnel, Brigitte" uniqKey="Kuhnel B" first="Brigitte" last="Kühnel">Brigitte Kühnel</name><affiliation wicri:level="1"><nlm:aff id="A57">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Lopez, Lorna M" sort="Lopez, Lorna M" uniqKey="Lopez L" first="Lorna M" last="Lopez">Lorna M. Lopez</name><affiliation wicri:level="4"><nlm:aff id="A58">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A59">Department of Psychology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Psychology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polašek">Ozren Polašek</name><affiliation wicri:level="1"><nlm:aff id="A60">Department of Public Health, Medical School, University of Split, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Department of Public Health, Medical School, University of Split, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Boban, Mladen" sort="Boban, Mladen" uniqKey="Boban M" first="Mladen" last="Boban">Mladen Boban</name><affiliation wicri:level="1"><nlm:aff id="A61">Department of Pharmacology, Medical School, University of Split, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Department of Pharmacology, Medical School, University of Split, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Nelson, Christopher P" sort="Nelson, Christopher P" uniqKey="Nelson C" first="Christopher P" last="Nelson">Christopher P. Nelson</name><affiliation wicri:level="1"><nlm:aff id="A62">Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation></author><author><name sortKey="Morrison, Alanna C" sort="Morrison, Alanna C" uniqKey="Morrison A" first="Alanna C" last="Morrison">Alanna C. Morrison</name><affiliation wicri:level="2"><nlm:aff id="A63">Division of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas at Houston Health Science Center, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas at Houston Health Science Center, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Pihur, Vasyl" sort="Pihur, Vasyl" uniqKey="Pihur V" first="Vasyl" last="Pihur">Vasyl Pihur</name><affiliation wicri:level="2"><nlm:aff id="A17">Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Ganesh, Santhi K" sort="Ganesh, Santhi K" uniqKey="Ganesh S" first="Santhi K" last="Ganesh">Santhi K. Ganesh</name><affiliation wicri:level="2"><nlm:aff id="A64">Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical Center, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Kundu, Suman" sort="Kundu, Suman" uniqKey="Kundu S" first="Suman" last="Kundu">Suman Kundu</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Mattace Raso, Francesco Us" sort="Mattace Raso, Francesco Us" uniqKey="Mattace Raso F" first="Francesco Us" last="Mattace-Raso">Francesco Us Mattace-Raso</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A3">Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><affiliation wicri:level="3"><nlm:aff id="A3">Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation><nlm:aff id="A4">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</nlm:aff></affiliation></author><author><name sortKey="Sijbrands, Eric Jg" sort="Sijbrands, Eric Jg" uniqKey="Sijbrands E" first="Eric Jg" last="Sijbrands">Eric Jg Sijbrands</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A3">Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="Andre G" last="Uitterlinden">Andre G. Uitterlinden</name><affiliation wicri:level="3"><nlm:aff id="A3">Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation><nlm:aff id="A4">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</nlm:aff></affiliation></author><author><name sortKey="Hwang, Shih Jen" sort="Hwang, Shih Jen" uniqKey="Hwang S" first="Shih-Jen" last="Hwang">Shih-Jen Hwang</name><affiliation wicri:level="2"><nlm:aff id="A9">Framingham Heart Study, Framingham, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A65">Center for Population Studies, National Heart Lung, and Blood Institute, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Population Studies, National Heart Lung, and Blood Institute, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A10">National Heart, Lung and Blood Institute, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Heart, Lung and Blood Institute, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Vasan, Ramachandran S" sort="Vasan, Ramachandran S" uniqKey="Vasan R" first="Ramachandran S" last="Vasan">Ramachandran S. Vasan</name><affiliation wicri:level="2"><nlm:aff id="A9">Framingham Heart Study, Framingham, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A66">Division of Epidemiology and Prevention, Boston University School of Medicine, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology and Prevention, Boston University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Wang, Thomas J" sort="Wang, Thomas J" uniqKey="Wang T" first="Thomas J" last="Wang">Thomas J. Wang</name><affiliation wicri:level="2"><nlm:aff id="A9">Framingham Heart Study, Framingham, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A67">Division of Cardiology, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cardiology, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Bergmann, Sven" sort="Bergmann, Sven" uniqKey="Bergmann S" first="Sven" last="Bergmann">Sven Bergmann</name><affiliation wicri:level="4"><nlm:aff id="A68">Département de Génétique Médicale, Université de Lausanne, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Département de Génétique Médicale, Université de Lausanne, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region><settlement type="city">Lausanne</settlement></placeName><orgName type="university">Université de Lausanne</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A69">Swiss Institute of Bioinformatics, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Swiss Institute of Bioinformatics, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Vollenweider, Peter" sort="Vollenweider, Peter" uniqKey="Vollenweider P" first="Peter" last="Vollenweider">Peter Vollenweider</name><affiliation wicri:level="3"><nlm:aff id="A70">Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Waeber, Gerard" sort="Waeber, Gerard" uniqKey="Waeber G" first="Gérard" last="Waeber">Gérard Waeber</name><affiliation wicri:level="3"><nlm:aff id="A70">Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Laitinen, Jaana" sort="Laitinen, Jaana" uniqKey="Laitinen J" first="Jaana" last="Laitinen">Jaana Laitinen</name><affiliation wicri:level="1"><nlm:aff id="A71">Finnish Institute of Occupational Health, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Finnish Institute of Occupational Health, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Pouta, Anneli" sort="Pouta, Anneli" uniqKey="Pouta A" first="Anneli" last="Pouta">Anneli Pouta</name><affiliation wicri:level="1"><nlm:aff id="A72">National Institute for Health and Welfare, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Zitting, Paavo" sort="Zitting, Paavo" uniqKey="Zitting P" first="Paavo" last="Zitting">Paavo Zitting</name><affiliation wicri:level="1"><nlm:aff id="A73">Department of Physiatrics, Lapland Central Hospital, Rovaniemi, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Physiatrics, Lapland Central Hospital, Rovaniemi</wicri:regionArea><wicri:noRegion>Rovaniemi</wicri:noRegion></affiliation></author><author><name sortKey="Mcardle, Wendy L" sort="Mcardle, Wendy L" uniqKey="Mcardle W" first="Wendy L" last="Mcardle">Wendy L. Mcardle</name><affiliation wicri:level="1"><nlm:aff id="A74">ALSPAC Laboratory, Department of Social Medicine, University of Bristol, Bristol, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>ALSPAC Laboratory, Department of Social Medicine, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Kroemer, Heyo K" sort="Kroemer, Heyo K" uniqKey="Kroemer H" first="Heyo K" last="Kroemer">Heyo K. Kroemer</name><affiliation wicri:level="1"><nlm:aff id="A75">Institute of Pharmacology, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Pharmacology, Ernst-Moritz-Arndt-University Greifswald, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Volker, Uwe" sort="Volker, Uwe" uniqKey="Volker U" first="Uwe" last="Völker">Uwe Völker</name><affiliation wicri:level="1"><nlm:aff id="A76">Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name><affiliation wicri:level="1"><nlm:aff id="A77">Institute for Community Medicine, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, Ernst-Moritz-Arndt-University Greifswald, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Glazer, Nicole L" sort="Glazer, Nicole L" uniqKey="Glazer N" first="Nicole L" last="Glazer">Nicole L. Glazer</name><affiliation wicri:level="2"><nlm:aff id="A78">Section of Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Section of Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Taylor, Kent D" sort="Taylor, Kent D" uniqKey="Taylor K" first="Kent D" last="Taylor">Kent D. Taylor</name><affiliation wicri:level="2"><nlm:aff id="A55">Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B" last="Harris">Tamara B. Harris</name><affiliation wicri:level="2"><nlm:aff id="A79">National Institute of Aging’s Laboratory for Epidemiology, Demography and Biometry, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute of Aging’s Laboratory for Epidemiology, Demography and Biometry, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Alavere, Helene" sort="Alavere, Helene" uniqKey="Alavere H" first="Helene" last="Alavere">Helene Alavere</name><affiliation wicri:level="1"><nlm:aff id="A27">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Haller, Toomas" sort="Haller, Toomas" uniqKey="Haller T" first="Toomas" last="Haller">Toomas Haller</name><affiliation wicri:level="1"><nlm:aff id="A27">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Keis, Aime" sort="Keis, Aime" uniqKey="Keis A" first="Aime" last="Keis">Aime Keis</name><affiliation wicri:level="1"><nlm:aff id="A27">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Tammesoo, Mari Liis" sort="Tammesoo, Mari Liis" uniqKey="Tammesoo M" first="Mari-Liis" last="Tammesoo">Mari-Liis Tammesoo</name><affiliation wicri:level="1"><nlm:aff id="A27">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Aulchenko, Yurii" sort="Aulchenko, Yurii" uniqKey="Aulchenko Y" first="Yurii" last="Aulchenko">Yurii Aulchenko</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Inês" last="Barroso">Inês Barroso</name><affiliation wicri:level="1"><nlm:aff id="A80">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A81">University of Cambridge Metabolic Research Labs, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University of Cambridge Metabolic Research Labs, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name><affiliation wicri:level="4"><nlm:aff id="A82">Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Galan, Pilar" sort="Galan, Pilar" uniqKey="Galan P" first="Pilar" last="Galan">Pilar Galan</name><affiliation wicri:level="3"><nlm:aff id="A83">U557 Institut National de la Santé et de la Recherche Médicale, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>U557 Institut National de la Santé et de la Recherche Médicale, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A84">U1125 Institut National de la Recherche Agronomique, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>U1125 Institut National de la Recherche Agronomique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A85">Université Paris 13, Bobigny, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Université Paris 13, Bobigny</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Bobigny</settlement><settlement type="city">Paris</settlement></placeName><orgName type="university">Université Paris 13</orgName></affiliation></author><author><name sortKey="Hercberg, Serge" sort="Hercberg, Serge" uniqKey="Hercberg S" first="Serge" last="Hercberg">Serge Hercberg</name><affiliation wicri:level="3"><nlm:aff id="A83">U557 Institut National de la Santé et de la Recherche Médicale, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>U557 Institut National de la Santé et de la Recherche Médicale, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A84">U1125 Institut National de la Recherche Agronomique, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>U1125 Institut National de la Recherche Agronomique, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A85">Université Paris 13, Bobigny, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Université Paris 13, Bobigny</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Bobigny</settlement><settlement type="city">Paris</settlement></placeName><orgName type="university">Université Paris 13</orgName></affiliation></author><author><name sortKey="Lathrop, Mark" sort="Lathrop, Mark" uniqKey="Lathrop M" first="Mark" last="Lathrop">Mark Lathrop</name><affiliation wicri:level="3"><nlm:aff id="A31">Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Centre National de Génotypage, Commissariat à L’Energie Atomique, Institut de Génomique, Evry</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Évry (Essonne)</settlement></placeName></affiliation></author><author><name sortKey="Eyheramendy, Susana" sort="Eyheramendy, Susana" uniqKey="Eyheramendy S" first="Susana" last="Eyheramendy">Susana Eyheramendy</name><affiliation wicri:level="1"><nlm:aff id="A86">Department of Statistics, Pontificia Universidad Catolica de Chile, Santiago, Chile</nlm:aff><country xml:lang="fr">Chili</country><wicri:regionArea>Department of Statistics, Pontificia Universidad Catolica de Chile, Santiago</wicri:regionArea><wicri:noRegion>Santiago</wicri:noRegion></affiliation></author><author><name sortKey="Org, Elin" sort="Org, Elin" uniqKey="Org E" first="Elin" last="Org">Elin Org</name><affiliation wicri:level="1"><nlm:aff id="A29">Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Institute of Molecular and Cell Biology, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="S Ber, Siim" sort="S Ber, Siim" uniqKey="S Ber S" first="Siim" last="S Ber">Siim S Ber</name><affiliation wicri:level="1"><nlm:aff id="A29">Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Institute of Molecular and Cell Biology, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Lu, Xiaowen" sort="Lu, Xiaowen" uniqKey="Lu X" first="Xiaowen" last="Lu">Xiaowen Lu</name><affiliation wicri:level="3"><nlm:aff id="A32">Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Nolte, Ilja M" sort="Nolte, Ilja M" uniqKey="Nolte I" first="Ilja M" last="Nolte">Ilja M. Nolte</name><affiliation wicri:level="3"><nlm:aff id="A32">Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Penninx, Brenda W" sort="Penninx, Brenda W" uniqKey="Penninx B" first="Brenda W" last="Penninx">Brenda W. Penninx</name><affiliation wicri:level="3"><nlm:aff id="A87">Department of Psychiatry/EMGO Institute/Neuroscience Campus, VU University Medical Centre, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Psychiatry/EMGO Institute/Neuroscience Campus, VU University Medical Centre, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A88">Department of Psychiatry, Leiden University Medical Centre, Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Psychiatry, Leiden University Medical Centre, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A89">Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Corre, Tanguy" sort="Corre, Tanguy" uniqKey="Corre T" first="Tanguy" last="Corre">Tanguy Corre</name><affiliation wicri:level="1"><nlm:aff id="A34">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Masciullo, Corrado" sort="Masciullo, Corrado" uniqKey="Masciullo C" first="Corrado" last="Masciullo">Corrado Masciullo</name><affiliation wicri:level="1"><nlm:aff id="A34">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Sala, Cinzia" sort="Sala, Cinzia" uniqKey="Sala C" first="Cinzia" last="Sala">Cinzia Sala</name><affiliation wicri:level="1"><nlm:aff id="A34">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Groop, Leif" sort="Groop, Leif" uniqKey="Groop L" first="Leif" last="Groop">Leif Groop</name><affiliation wicri:level="1"><nlm:aff id="A90">Department of Clinical Sciences, Diabetes and Endocrinology Research Unit, Lund University, University Hospital Malmö, Malmö, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Sciences, Diabetes and Endocrinology Research Unit, Lund University, University Hospital Malmö, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Voight, Benjamin F" sort="Voight, Benjamin F" uniqKey="Voight B" first="Benjamin F" last="Voight">Benjamin F. Voight</name><affiliation wicri:level="2"><nlm:aff id="A91">Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Melander, Olle" sort="Melander, Olle" uniqKey="Melander O" first="Olle" last="Melander">Olle Melander</name><affiliation wicri:level="1"><nlm:aff id="A92">Department of Clinical Sciences, Hypertension and Cardiovascular Diseases, University Hospital, Malmö, Lund University, Malmö 20502, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Sciences, Hypertension and Cardiovascular Diseases, University Hospital, Malmö, Lund University, Malmö 20502</wicri:regionArea><wicri:noRegion>Malmö 20502</wicri:noRegion></affiliation></author><author><name sortKey="O Onnell, Christopher J" sort="O Onnell, Christopher J" uniqKey="O Onnell C" first="Christopher J" last="O Onnell">Christopher J. O Onnell</name><affiliation><nlm:aff id="A93">National Heart, Lung and Blood Institute and its Framingham Heart Study, 73 Mount Wayte Ave., Suite</nlm:aff><wicri:noCountry code="subfield">Suite</wicri:noCountry></affiliation></author><author><name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name><affiliation wicri:level="1"><nlm:aff id="A94">Department of Chronic Disease Prevention, THL-National Institute for Health and Welfare, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Chronic Disease Prevention, THL-National Institute for Health and Welfare, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="D Damo, Adamo Pio" sort="D Damo, Adamo Pio" uniqKey="D Damo A" first="Adamo Pio" last="D Damo">Adamo Pio D Damo</name><affiliation wicri:level="1"><nlm:aff id="A37">Medical Genetics IRCCS Burlo Garofolo/Università degli Studi di Trieste, Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Medical Genetics IRCCS Burlo Garofolo/Università degli Studi di Trieste, Trieste</wicri:regionArea><wicri:noRegion>Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Fabretto, Antonella" sort="Fabretto, Antonella" uniqKey="Fabretto A" first="Antonella" last="Fabretto">Antonella Fabretto</name><affiliation wicri:level="1"><nlm:aff id="A95">IRCSS Burlo Garofolo Medical Genetics, Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>IRCSS Burlo Garofolo Medical Genetics, Trieste</wicri:regionArea><wicri:noRegion>Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Faletra, Flavio" sort="Faletra, Flavio" uniqKey="Faletra F" first="Flavio" last="Faletra">Flavio Faletra</name><affiliation wicri:level="1"><nlm:aff id="A95">IRCSS Burlo Garofolo Medical Genetics, Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>IRCSS Burlo Garofolo Medical Genetics, Trieste</wicri:regionArea><wicri:noRegion>Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Ulivi, Sheila" sort="Ulivi, Sheila" uniqKey="Ulivi S" first="Sheila" last="Ulivi">Sheila Ulivi</name><affiliation wicri:level="1"><nlm:aff id="A37">Medical Genetics IRCCS Burlo Garofolo/Università degli Studi di Trieste, Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Medical Genetics IRCCS Burlo Garofolo/Università degli Studi di Trieste, Trieste</wicri:regionArea><wicri:noRegion>Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Del Greco, M Fabiola" sort="Del Greco, M Fabiola" uniqKey="Del Greco M" first="M Fabiola" last="Del Greco">M Fabiola Del Greco</name><affiliation wicri:level="1"><nlm:aff id="A38">Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy. Affiliated Institute of the University of Lübeck, Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy. Affiliated Institute of the University of Lübeck, Lübeck</wicri:regionArea><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion></affiliation></author><author><name sortKey="Facheris, Maurizio" sort="Facheris, Maurizio" uniqKey="Facheris M" first="Maurizio" last="Facheris">Maurizio Facheris</name><affiliation wicri:level="1"><nlm:aff id="A38">Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy. Affiliated Institute of the University of Lübeck, Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy. Affiliated Institute of the University of Lübeck, Lübeck</wicri:regionArea><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion></affiliation></author><author><name sortKey="Collins, Francis S" sort="Collins, Francis S" uniqKey="Collins F" first="Francis S" last="Collins">Francis S. Collins</name><affiliation wicri:level="2"><nlm:aff id="A96">National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Bergman, Richard N" sort="Bergman, Richard N" uniqKey="Bergman R" first="Richard N" last="Bergman">Richard N. Bergman</name><affiliation wicri:level="4"><nlm:aff id="A97">Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Beilby, John P" sort="Beilby, John P" uniqKey="Beilby J" first="John P" last="Beilby">John P. Beilby</name><affiliation wicri:level="1"><nlm:aff id="A98">Pathology and Laboratory Medicine, University of Western Australia, Crawley, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Pathology and Laboratory Medicine, University of Western Australia, Crawley, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A99">Molecular Genetics, PathWest Laboratory Medicine, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Molecular Genetics, PathWest Laboratory Medicine, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A100">Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Hung, Joseph" sort="Hung, Joseph" uniqKey="Hung J" first="Joseph" last="Hung">Joseph Hung</name><affiliation wicri:level="1"><nlm:aff id="A101">School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A100">Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Musk, A William" sort="Musk, A William" uniqKey="Musk A" first="A William" last="Musk">A William Musk</name><affiliation wicri:level="1"><nlm:aff id="A100">Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A102">School of Medicine and Pharmcology, University of Western Australia, Crawley, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Medicine and Pharmcology, University of Western Australia, Crawley, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A103">Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name><affiliation wicri:level="3"><nlm:aff id="A41">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Shin, So Youn" sort="Shin, So Youn" uniqKey="Shin S" first="So-Youn" last="Shin">So-Youn Shin</name><affiliation wicri:level="1"><nlm:aff id="A80">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A41">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Soranzo, Nicole" sort="Soranzo, Nicole" uniqKey="Soranzo N" first="Nicole" last="Soranzo">Nicole Soranzo</name><affiliation wicri:level="1"><nlm:aff id="A80">Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A41">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Watkins, Hugh" sort="Watkins, Hugh" uniqKey="Watkins H" first="Hugh" last="Watkins">Hugh Watkins</name><affiliation wicri:level="4"><nlm:aff id="A42">Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A43">Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Goel, Anuj" sort="Goel, Anuj" uniqKey="Goel A" first="Anuj" last="Goel">Anuj Goel</name><affiliation wicri:level="4"><nlm:aff id="A42">Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A43">Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name><affiliation wicri:level="3"><nlm:aff id="A104">Atherosclerosis Research Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Atherosclerosis Research Unit, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Gider, Pierre" sort="Gider, Pierre" uniqKey="Gider P" first="Pierre" last="Gider">Pierre Gider</name><affiliation wicri:level="1"><nlm:aff id="A44">Institute of Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria</nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea>Institute of Molecular Biology and Biochemistry, Medical University Graz, Graz</wicri:regionArea><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Loitfelder, Marisa" sort="Loitfelder, Marisa" uniqKey="Loitfelder M" first="Marisa" last="Loitfelder">Marisa Loitfelder</name><affiliation wicri:level="1"><nlm:aff id="A105">Department of Neurology Section of Special Neurology, Medical University Graz, Graz, Austria</nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology Section of Special Neurology, Medical University Graz, Graz</wicri:regionArea><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Zeginigg, Marion" sort="Zeginigg, Marion" uniqKey="Zeginigg M" first="Marion" last="Zeginigg">Marion Zeginigg</name><affiliation wicri:level="1"><nlm:aff id="A44">Institute of Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria</nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea>Institute of Molecular Biology and Biochemistry, Medical University Graz, Graz</wicri:regionArea><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Hernandez, Dena" sort="Hernandez, Dena" uniqKey="Hernandez D" first="Dena" last="Hernandez">Dena Hernandez</name><affiliation wicri:level="2"><nlm:aff id="A106">National Institute of Aging’s Laboratory of Neurogenetics, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute of Aging’s Laboratory of Neurogenetics, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Najjar, Samer S" sort="Najjar, Samer S" uniqKey="Najjar S" first="Samer S" last="Najjar">Samer S. Najjar</name><affiliation wicri:level="2"><nlm:aff id="A107">Laboratory of Cardiovascular Science, Intramural Research Program, National Institute on Aging, NIH, Baltimore, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Cardiovascular Science, Intramural Research Program, National Institute on Aging, NIH, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A108">Cardiovascular Research Institute, MedStar Health Research Institute, Washington Hospital Center, Washington DC, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Research Institute, MedStar Health Research Institute, Washington Hospital Center, Washington DC</wicri:regionArea><placeName><settlement type="city">Washington (district de Columbia)</settlement><region type="state">District de Columbia</region></placeName></affiliation></author><author><name sortKey="Navarro, Pau" sort="Navarro, Pau" uniqKey="Navarro P" first="Pau" last="Navarro">Pau Navarro</name><affiliation wicri:level="3"><nlm:aff id="A49">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Wild, Sarah H" sort="Wild, Sarah H" uniqKey="Wild S" first="Sarah H" last="Wild">Sarah H. Wild</name><affiliation wicri:level="4"><nlm:aff id="A46">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Corsi, Anna Maria" sort="Corsi, Anna Maria" uniqKey="Corsi A" first="Anna Maria" last="Corsi">Anna Maria Corsi</name><affiliation wicri:level="1"><nlm:aff id="A109">Tuscany Regional Health Agency, Florence, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Tuscany Regional Health Agency, Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation></author><author><name sortKey="Singleton, Andrew" sort="Singleton, Andrew" uniqKey="Singleton A" first="Andrew" last="Singleton">Andrew Singleton</name><affiliation wicri:level="2"><nlm:aff id="A106">National Institute of Aging’s Laboratory of Neurogenetics, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute of Aging’s Laboratory of Neurogenetics, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="De Geus, Eco Jc" sort="De Geus, Eco Jc" uniqKey="De Geus E" first="Eco Jc" last="De Geus">Eco Jc De Geus</name><affiliation wicri:level="3"><nlm:aff id="A110">EMGO+ institute, Department of Biological Psychology, VU University, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>EMGO+ institute, Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Willemsen, Gonneke" sort="Willemsen, Gonneke" uniqKey="Willemsen G" first="Gonneke" last="Willemsen">Gonneke Willemsen</name><affiliation wicri:level="3"><nlm:aff id="A110">EMGO+ institute, Department of Biological Psychology, VU University, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>EMGO+ institute, Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Parker, Alex N" sort="Parker, Alex N" uniqKey="Parker A" first="Alex N" last="Parker">Alex N. Parker</name><affiliation wicri:level="2"><nlm:aff id="A111">Amgen, Cambridge, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Amgen, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Rose, Lynda M" sort="Rose, Lynda M" uniqKey="Rose L" first="Lynda M" last="Rose">Lynda M. Rose</name><affiliation wicri:level="2"><nlm:aff id="A50">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Buckley, Brendan" sort="Buckley, Brendan" uniqKey="Buckley B" first="Brendan" last="Buckley">Brendan Buckley</name><affiliation wicri:level="1"><nlm:aff id="A112">Department of Pharmacology and Therapeutics, University College Cork, Cork, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Pharmacology and Therapeutics, University College Cork, Cork</wicri:regionArea><wicri:noRegion>Cork</wicri:noRegion></affiliation></author><author><name sortKey="Stott, David" sort="Stott, David" uniqKey="Stott D" first="David" last="Stott">David Stott</name><affiliation wicri:level="4"><nlm:aff id="A113">Institute of Cardiovascular and Medical Sciences, School of Medicine, University of Glasgow, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Cardiovascular and Medical Sciences, School of Medicine, University of Glasgow</wicri:regionArea><placeName><settlement type="city">Glasgow</settlement><region type="country">Écosse</region></placeName><orgName type="university">Université de Glasgow</orgName></affiliation></author><author><name sortKey="Orru, Marco" sort="Orru, Marco" uniqKey="Orru M" first="Marco" last="Orru">Marco Orru</name><affiliation wicri:level="1"><nlm:aff id="A114">Istituto di Neurogenetica e Neurofarmacologia, Consiglio Nazionale delle Ricerche, Monserrato, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto di Neurogenetica e Neurofarmacologia, Consiglio Nazionale delle Ricerche, Monserrato</wicri:regionArea><wicri:noRegion>Monserrato</wicri:noRegion></affiliation></author><author><name sortKey="Uda, Manuela" sort="Uda, Manuela" uniqKey="Uda M" first="Manuela" last="Uda">Manuela Uda</name><affiliation wicri:level="1"><nlm:aff id="A114">Istituto di Neurogenetica e Neurofarmacologia, Consiglio Nazionale delle Ricerche, Monserrato, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto di Neurogenetica e Neurofarmacologia, Consiglio Nazionale delle Ricerche, Monserrato</wicri:regionArea><wicri:noRegion>Monserrato</wicri:noRegion></affiliation></author><author><name sortKey="Van Der Klauw, Melanie M" sort="Van Der Klauw, Melanie M" uniqKey="Van Der Klauw M" first="Melanie M" last="Van Der Klauw">Melanie M. Van Der Klauw</name><affiliation wicri:level="4"><nlm:aff id="A115">Department of Endocrinology, University Medical Center Groningen, University of Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Endocrinology, University Medical Center Groningen, University of Groningen</wicri:regionArea><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName><orgName type="university">Université de Groningue</orgName></affiliation></author><author><name sortKey="Zhang, Weihua" sort="Zhang, Weihua" uniqKey="Zhang W" first="Weihua" last="Zhang">Weihua Zhang</name><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A54">Ealing Hospital NHS Trust, Middlesex, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ealing Hospital NHS Trust, Middlesex</wicri:regionArea><wicri:noRegion>Middlesex</wicri:noRegion></affiliation></author><author><name sortKey="Li, Xinzhong" sort="Li, Xinzhong" uniqKey="Li X" first="Xinzhong" last="Li">Xinzhong Li</name><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Scott, James" sort="Scott, James" uniqKey="Scott J" first="James" last="Scott">James Scott</name><affiliation wicri:level="3"><nlm:aff id="A116">National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Chen, Yii Der Ida" sort="Chen, Yii Der Ida" uniqKey="Chen Y" first="Yii-Der Ida" last="Chen">Yii-Der Ida Chen</name><affiliation wicri:level="2"><nlm:aff id="A55">Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Burke, Gregory L" sort="Burke, Gregory L" uniqKey="Burke G" first="Gregory L" last="Burke">Gregory L. Burke</name><affiliation wicri:level="2"><nlm:aff id="A117">Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="K Honen, Mika" sort="K Honen, Mika" uniqKey="K Honen M" first="Mika" last="K Hönen">Mika K Hönen</name><affiliation wicri:level="1"><nlm:aff id="A118">Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere</wicri:regionArea><wicri:noRegion>Tampere</wicri:noRegion></affiliation></author><author><name sortKey="Viikari, Jorma" sort="Viikari, Jorma" uniqKey="Viikari J" first="Jorma" last="Viikari">Jorma Viikari</name><affiliation wicri:level="3"><nlm:aff id="A119">Department of Medicine, University of Turku and Turku University Hospital, Turku, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Medicine, University of Turku and Turku University Hospital, Turku</wicri:regionArea><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region></placeName></affiliation></author><author><name sortKey="Doring, Angela" sort="Doring, Angela" uniqKey="Doring A" first="Angela" last="Döring">Angela Döring</name><affiliation wicri:level="1"><nlm:aff id="A120">Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A121">Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Meitinger, Thomas" sort="Meitinger, Thomas" uniqKey="Meitinger T" first="Thomas" last="Meitinger">Thomas Meitinger</name><affiliation wicri:level="1"><nlm:aff id="A122">Institute of Human Genetics, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A123">Institute of Human Genetics, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Davies, Gail" sort="Davies, Gail" uniqKey="Davies G" first="Gail" last="Davies">Gail Davies</name><affiliation wicri:level="4"><nlm:aff id="A59">Department of Psychology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Psychology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Starr, John M" sort="Starr, John M" uniqKey="Starr J" first="John M" last="Starr">John M. Starr</name><affiliation wicri:level="4"><nlm:aff id="A58">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A124">Geriatric Medicine Unit, The University of Edinburgh, Royal Victoria, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Geriatric Medicine Unit, The University of Edinburgh, Royal Victoria, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Emilsson, Valur" sort="Emilsson, Valur" uniqKey="Emilsson V" first="Valur" last="Emilsson">Valur Emilsson</name><affiliation wicri:level="1"><nlm:aff id="A15">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation></author><author><name sortKey="Plump, Andrew" sort="Plump, Andrew" uniqKey="Plump A" first="Andrew" last="Plump">Andrew Plump</name><affiliation wicri:level="2"><nlm:aff id="A125">Cardiovascular Disease Franchise, Merck Research Laboratory, Rahway, New Jersey, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Disease Franchise, Merck Research Laboratory, Rahway, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Lindeman, Jan H" sort="Lindeman, Jan H" uniqKey="Lindeman J" first="Jan H" last="Lindeman">Jan H. Lindeman</name><affiliation wicri:level="3"><nlm:aff id="A126">Department of Vascular Surgery, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Vascular Surgery, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey=" Hoen, Peter Ac" sort=" Hoen, Peter Ac" uniqKey=" Hoen P" first="Peter Ac" last=" Hoen">Peter Ac Hoen</name><affiliation wicri:level="3"><nlm:aff id="A127">Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Human Genetics, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A128">Leiden Genome Technology Center, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Leiden Genome Technology Center, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Konig, Inke R" sort="Konig, Inke R" uniqKey="Konig I" first="Inke R" last="König">Inke R. König</name><affiliation wicri:level="1"><nlm:aff id="A129">Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Lübeck</wicri:regionArea><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion></affiliation></author><author><name sortKey="Felix, Janine F" sort="Felix, Janine F" uniqKey="Felix J" first="Janine F" last="Felix">Janine F. Felix</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation><nlm:aff id="A4">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</nlm:aff></affiliation><affiliation wicri:level="3"><nlm:aff id="A130">German Cancer Research Center, Division of Clinical Epidemiology and Aging Research, Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Cancer Research Center, Division of Clinical Epidemiology and Aging Research, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Clarke, Robert" sort="Clarke, Robert" uniqKey="Clarke R" first="Robert" last="Clarke">Robert Clarke</name><affiliation wicri:level="4"><nlm:aff id="A131">Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Hopewell, Jemma C" sort="Hopewell, Jemma C" uniqKey="Hopewell J" first="Jemma C" last="Hopewell">Jemma C. Hopewell</name><affiliation wicri:level="4"><nlm:aff id="A131">Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Ongen, Halit" sort="Ongen, Halit" uniqKey="Ongen H" first="Halit" last="Ongen">Halit Ongen</name><affiliation wicri:level="4"><nlm:aff id="A42">Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Breteler, Monique" sort="Breteler, Monique" uniqKey="Breteler M" first="Monique" last="Breteler">Monique Breteler</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Debette, Stephanie" sort="Debette, Stephanie" uniqKey="Debette S" first="Stéphanie" last="Debette">Stéphanie Debette</name><affiliation wicri:level="2"><nlm:aff id="A132">Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Boston University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Destefano, Anita L" sort="Destefano, Anita L" uniqKey="Destefano A" first="Anita L" last="Destefano">Anita L. Destefano</name><affiliation wicri:level="2"><nlm:aff id="A133">Boston University School of Public Health, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Fornage, Myriam" sort="Fornage, Myriam" uniqKey="Fornage M" first="Myriam" last="Fornage">Myriam Fornage</name><affiliation wicri:level="2"><nlm:aff id="A134">Brown Foundation Institute of Molecular Medicine and Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Brown Foundation Institute of Molecular Medicine and Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Mitchell, Gary F" sort="Mitchell, Gary F" uniqKey="Mitchell G" first="Gary F" last="Mitchell">Gary F. Mitchell</name><affiliation wicri:level="2"><nlm:aff id="A135">Cardiovascular Engineering, Inc., Norwood, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Engineering, Inc., Norwood, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Smith, Nicholas L" sort="Smith, Nicholas L" uniqKey="Smith N" first="Nicholas L" last="Smith">Nicholas L. Smith</name><affiliation wicri:level="4"><nlm:aff id="A136">Department of Epidemiology, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="2"><nlm:aff id="A137">Seattle Epidemiologic Research and Information, Center of the Department of Veterans Affairs Office of Research and Development, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Seattle Epidemiologic Research and Information, Center of the Department of Veterans Affairs Office of Research and Development, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A138">Group Health Research Institute, Group Health Cooperative, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Group Health Research Institute, Group Health Cooperative, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Holm, Hilma" sort="Holm, Hilma" uniqKey="Holm H" first="Hilma" last="Holm">Hilma Holm</name><affiliation wicri:level="1"><nlm:aff id="A139">deCODE genetics Inc, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE genetics Inc, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Stefansson, Kari" sort="Stefansson, Kari" uniqKey="Stefansson K" first="Kari" last="Stefansson">Kari Stefansson</name><affiliation wicri:level="1"><nlm:aff id="A139">deCODE genetics Inc, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE genetics Inc, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A140">Faculty of Medicine, University of Iceland, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Thorleifsson, Gudmar" sort="Thorleifsson, Gudmar" uniqKey="Thorleifsson G" first="Gudmar" last="Thorleifsson">Gudmar Thorleifsson</name><affiliation wicri:level="1"><nlm:aff id="A139">deCODE genetics Inc, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE genetics Inc, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Thorsteinsdottir, Unnur" sort="Thorsteinsdottir, Unnur" uniqKey="Thorsteinsdottir U" first="Unnur" last="Thorsteinsdottir">Unnur Thorsteinsdottir</name><affiliation wicri:level="1"><nlm:aff id="A139">deCODE genetics Inc, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE genetics Inc, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A140">Faculty of Medicine, University of Iceland, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Samani, Nilesh J" sort="Samani, Nilesh J" uniqKey="Samani N" first="Nilesh J" last="Samani">Nilesh J. Samani</name><affiliation wicri:level="1"><nlm:aff id="A62">Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A141">Leicester NIHR Biomedical Research Unit in Cardiovascular Disease, Glenfield Hospital, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Leicester NIHR Biomedical Research Unit in Cardiovascular Disease, Glenfield Hospital, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation></author><author><name sortKey="Preuss, Michael" sort="Preuss, Michael" uniqKey="Preuss M" first="Michael" last="Preuss">Michael Preuss</name><affiliation wicri:level="1"><nlm:aff id="A142">Medizinische Klinik II, Universität zu Lübeck, Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Medizinische Klinik II, Universität zu Lübeck, Lübeck</wicri:regionArea><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A129">Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Lübeck</wicri:regionArea><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation wicri:level="4"><nlm:aff id="A46">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A143">Croatian Centre for Global Health, University of Split Medical School, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Croatian Centre for Global Health, University of Split Medical School, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><affiliation wicri:level="3"><nlm:aff id="A49">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Deary, Ian J" sort="Deary, Ian J" uniqKey="Deary I" first="Ian J" last="Deary">Ian J. Deary</name><affiliation wicri:level="4"><nlm:aff id="A58">Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A59">Department of Psychology, The University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Psychology, The University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Wichmann, H Erich" sort="Wichmann, H Erich" uniqKey="Wichmann H" first="H-Erich" last="Wichmann">H-Erich Wichmann</name><affiliation wicri:level="1"><nlm:aff id="A120">Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A144">Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität and Klinikum Grosshadern, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität and Klinikum Grosshadern, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Raitakari, Olli T" sort="Raitakari, Olli T" uniqKey="Raitakari O" first="Olli T" last="Raitakari">Olli T. Raitakari</name><affiliation wicri:level="3"><nlm:aff id="A145">Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku and the Department of Clinical Physiology, Turku University Hospital, Turku, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku and the Department of Clinical Physiology, Turku University Hospital, Turku</wicri:regionArea><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region></placeName></affiliation></author><author><name sortKey="Palmas, Walter" sort="Palmas, Walter" uniqKey="Palmas W" first="Walter" last="Palmas">Walter Palmas</name><affiliation wicri:level="4"><nlm:aff id="A146">Columbia University, New York, New York, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Columbia University, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Kooner, Jaspal S" sort="Kooner, Jaspal S" uniqKey="Kooner J" first="Jaspal S" last="Kooner">Jaspal S. Kooner</name><affiliation wicri:level="3"><nlm:aff id="A116">National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A54">Ealing Hospital NHS Trust, Middlesex, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Ealing Hospital NHS Trust, Middlesex</wicri:regionArea><wicri:noRegion>Middlesex</wicri:noRegion></affiliation></author><author><name sortKey="Stolk, Ronald P" sort="Stolk, Ronald P" uniqKey="Stolk R" first="Ronald P" last="Stolk">Ronald P. Stolk</name><affiliation wicri:level="4"><nlm:aff id="A147">Department of Epidemiology, University Medical Center Groningen, University of Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, University Medical Center Groningen, University of Groningen</wicri:regionArea><placeName><settlement type="city">Groningue (ville)</settlement><region>Groningue (province)</region></placeName><orgName type="university">Université de Groningue</orgName></affiliation></author><author><name sortKey="Jukema, J Wouter" sort="Jukema, J Wouter" uniqKey="Jukema J" first="J Wouter" last="Jukema">J Wouter Jukema</name><affiliation wicri:level="3"><nlm:aff id="A52">Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Cardiology, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A148">Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Durrer Center for Cardiogenetic Research, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A149">Interuniversity Cardiology Institute of the Netherlands, Utrecht, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Interuniversity Cardiology Institute of the Netherlands, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F" last="Wright">Alan F. Wright</name><affiliation wicri:level="3"><nlm:aff id="A49">MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I" last="Boomsma">Dorret I. Boomsma</name><affiliation wicri:level="3"><nlm:aff id="A110">EMGO+ institute, Department of Biological Psychology, VU University, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>EMGO+ institute, Department of Biological Psychology, VU University, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Bandinelli, Stefania" sort="Bandinelli, Stefania" uniqKey="Bandinelli S" first="Stefania" last="Bandinelli">Stefania Bandinelli</name><affiliation wicri:level="1"><nlm:aff id="A150">Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation></author><author><name sortKey="Gyllensten, Ulf B" sort="Gyllensten, Ulf B" uniqKey="Gyllensten U" first="Ulf B" last="Gyllensten">Ulf B. Gyllensten</name><affiliation wicri:level="4"><nlm:aff id="A47">Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><affiliation wicri:level="4"><nlm:aff id="A46">Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Population Health Sciences, University of Edinburgh, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region><settlement type="city">Édimbourg</settlement></placeName><orgName type="university">Université d'Édimbourg</orgName></affiliation></author><author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name><affiliation wicri:level="2"><nlm:aff id="A45">Clinical Research Branch, National Institute on Aging, Baltimore, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Clinical Research Branch, National Institute on Aging, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Schmidt, Reinhold" sort="Schmidt, Reinhold" uniqKey="Schmidt R" first="Reinhold" last="Schmidt">Reinhold Schmidt</name><affiliation wicri:level="1"><nlm:aff id="A105">Department of Neurology Section of Special Neurology, Medical University Graz, Graz, Austria</nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology Section of Special Neurology, Medical University Graz, Graz</wicri:regionArea><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Farrall, Martin" sort="Farrall, Martin" uniqKey="Farrall M" first="Martin" last="Farrall">Martin Farrall</name><affiliation wicri:level="4"><nlm:aff id="A42">Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A43">Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D" last="Spector">Tim D. Spector</name><affiliation wicri:level="3"><nlm:aff id="A41">Department of Twin Research and Genetic Epidemiology, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Palmer, Lyle J" sort="Palmer, Lyle J" uniqKey="Palmer L" first="Lyle J" last="Palmer">Lyle J. Palmer</name><affiliation wicri:level="1"><nlm:aff id="A40">Centre for Genetic Epidemiology and Biostatistics, University of Western Australia, Crawley, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Genetic Epidemiology and Biostatistics, University of Western Australia, Crawley, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A100">Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Busselton Population Medical Research Foundation, Sir Charles Gairdner Hospital, Nedlands, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A151">Ontario Institute for Cancer Research, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Ontario Institute for Cancer Research, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A152">Samuel Lunenfeld Research Institute, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Samuel Lunenfeld Research Institute, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation></author><author><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name><affiliation wicri:level="1"><nlm:aff id="A153">National Institute for Health and Welfare, Diabetes Prevention Unit, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Diabetes Prevention Unit, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A154">Hjelt Institute, Department of Public Health, University of Helsinki, 00014 Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Hjelt Institute, Department of Public Health, University of Helsinki, 00014 Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A155">South Ostrobothnia Central Hospital, Seinajoki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>South Ostrobothnia Central Hospital, Seinajoki</wicri:regionArea><wicri:noRegion>Seinajoki</wicri:noRegion></affiliation></author><author><name sortKey="Pfeufer, Arne" sort="Pfeufer, Arne" uniqKey="Pfeufer A" first="Arne" last="Pfeufer">Arne Pfeufer</name><affiliation wicri:level="1"><nlm:aff id="A38">Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy. Affiliated Institute of the University of Lübeck, Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Medicine, European Academy Bozen/Bolzano (EURAC), Bolzano, Italy. Affiliated Institute of the University of Lübeck, Lübeck</wicri:regionArea><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A156">Institute of Human Genetics, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Klinikum rechts der Isar der Technischen Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A157">Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Gasparini, Paolo" sort="Gasparini, Paolo" uniqKey="Gasparini P" first="Paolo" last="Gasparini">Paolo Gasparini</name><affiliation wicri:level="1"><nlm:aff id="A95">IRCSS Burlo Garofolo Medical Genetics, Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>IRCSS Burlo Garofolo Medical Genetics, Trieste</wicri:regionArea><wicri:noRegion>Trieste</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A37">Medical Genetics IRCCS Burlo Garofolo/Università degli Studi di Trieste, Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Medical Genetics IRCCS Burlo Garofolo/Università degli Studi di Trieste, Trieste</wicri:regionArea><wicri:noRegion>Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Siscovick, David" sort="Siscovick, David" uniqKey="Siscovick D" first="David" last="Siscovick">David Siscovick</name><affiliation wicri:level="4"><nlm:aff id="A158">Department of Medicine, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A136">Department of Epidemiology, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A26">Cardiovascular Health Research Unit, Division of Internal Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, Division of Internal Medicine, Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Altshuler, David" sort="Altshuler, David" uniqKey="Altshuler D" first="David" last="Altshuler">David Altshuler</name><affiliation wicri:level="2"><nlm:aff id="A159">Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A160">Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A91">Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A161">Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Loos, Ruth Jf" sort="Loos, Ruth Jf" uniqKey="Loos R" first="Ruth Jf" last="Loos">Ruth Jf Loos</name><affiliation wicri:level="1"><nlm:aff id="A30">MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Toniolo, Daniela" sort="Toniolo, Daniela" uniqKey="Toniolo D" first="Daniela" last="Toniolo">Daniela Toniolo</name><affiliation wicri:level="1"><nlm:aff id="A34">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A162">Institute of Molecuar Genetics_CNR, Pavia, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Molecuar Genetics_CNR, Pavia</wicri:regionArea><wicri:noRegion>Pavia</wicri:noRegion></affiliation></author><author><name sortKey="Snieder, Harold" sort="Snieder, Harold" uniqKey="Snieder H" first="Harold" last="Snieder">Harold Snieder</name><affiliation wicri:level="3"><nlm:aff id="A32">Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Unit of Genetic Epidemiology and Bioinformatics, Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:aff id="A57">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg</wicri:regionArea><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion><wicri:noRegion>Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Meneton, Pierre" sort="Meneton, Pierre" uniqKey="Meneton P" first="Pierre" last="Meneton">Pierre Meneton</name><affiliation wicri:level="3"><nlm:aff id="A163">U872 Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, Paris, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>U872 Institut National de la Santé et de la Recherche Médicale, Centre de Recherche des Cordeliers, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J" last="Wareham">Nicholas J. Wareham</name><affiliation wicri:level="1"><nlm:aff id="A30">MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Oostra, Ben A" sort="Oostra, Ben A" uniqKey="Oostra B" first="Ben A" last="Oostra">Ben A. Oostra</name><affiliation wicri:level="3"><nlm:aff id="A164">Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name><affiliation wicri:level="1"><nlm:aff id="A27">Estonian Genome Center, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A28">Estonian Biocenter, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Biocenter, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A29">Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Institute of Molecular and Cell Biology, University of Tartu, Tartu</wicri:regionArea><wicri:noRegion>Tartu</wicri:noRegion></affiliation></author><author><name sortKey="Launer, Lenore" sort="Launer, Lenore" uniqKey="Launer L" first="Lenore" last="Launer">Lenore Launer</name><affiliation wicri:level="1"><nlm:aff id="A165">National Institute of Aging’s Laboratory for Epidemiology, Demography and Biometry, Bethesda, Marylands, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute of Aging’s Laboratory for Epidemiology, Demography and Biometry, Bethesda, Marylands</wicri:regionArea><wicri:noRegion>Marylands</wicri:noRegion></affiliation></author><author><name sortKey="Rettig, Rainer" sort="Rettig, Rainer" uniqKey="Rettig R" first="Rainer" last="Rettig">Rainer Rettig</name><affiliation wicri:level="1"><nlm:aff id="A166">Institute of Physiology, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Physiology, Ernst-Moritz-Arndt-University Greifswald, Greifswald</wicri:regionArea><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion><wicri:noRegion>Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Strachan, David P" sort="Strachan, David P" uniqKey="Strachan D" first="David P" last="Strachan">David P. Strachan</name><affiliation wicri:level="4"><nlm:aff id="A23">Division of Community Health Sciences, St George’s, University of London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Community Health Sciences, St George’s, University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Beckmann, Jacques S" sort="Beckmann, Jacques S" uniqKey="Beckmann J" first="Jacques S" last="Beckmann">Jacques S. Beckmann</name><affiliation wicri:level="4"><nlm:aff id="A68">Département de Génétique Médicale, Université de Lausanne, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Département de Génétique Médicale, Université de Lausanne, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region><settlement type="city">Lausanne</settlement></placeName><orgName type="university">Université de Lausanne</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A167">Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Witteman, Jacqueline Cm" sort="Witteman, Jacqueline Cm" uniqKey="Witteman J" first="Jacqueline Cm" last="Witteman">Jacqueline Cm Witteman</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation><nlm:aff id="A4">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</nlm:aff></affiliation></author><author><name sortKey="Erdmann, Jeanette" sort="Erdmann, Jeanette" uniqKey="Erdmann J" first="Jeanette" last="Erdmann">Jeanette Erdmann</name><affiliation wicri:level="1"><nlm:aff id="A142">Medizinische Klinik II, Universität zu Lübeck, Lübeck, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Medizinische Klinik II, Universität zu Lübeck, Lübeck</wicri:regionArea><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion><wicri:noRegion>Lübeck</wicri:noRegion></affiliation></author><author><name sortKey="Van Dijk, Ko Willems" sort="Van Dijk, Ko Willems" uniqKey="Van Dijk K" first="Ko Willems" last="Van Dijk">Ko Willems Van Dijk</name><affiliation wicri:level="3"><nlm:aff id="A14">Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Human Genetics, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A168">Department of Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><affiliation wicri:level="2"><nlm:aff id="A169">Human Genetics Center, Houston, Texas, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genetics Center, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Boehnke, Michael" sort="Boehnke, Michael" uniqKey="Boehnke M" first="Michael" last="Boehnke">Michael Boehnke</name><affiliation wicri:level="2"><nlm:aff id="A39">Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M" last="Ridker">Paul M. Ridker</name><affiliation wicri:level="2"><nlm:aff id="A50">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A170">Division of Cardiology, Brigham and Women’s Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cardiology, Brigham and Women’s Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A51">Harvard Medical School, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A72">National Institute for Health and Welfare, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>National Institute for Health and Welfare, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Jarvelin, Marjo Riitta" sort="Jarvelin, Marjo Riitta" uniqKey="Jarvelin M" first="Marjo-Riitta" last="Jarvelin">Marjo-Riitta Jarvelin</name><affiliation wicri:level="3"><nlm:aff id="A171">Department of Biostatistics and Epidemiology, School of Public Health, Imperial College London, Norfolk Place, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Biostatistics and Epidemiology, School of Public Health, Imperial College London, Norfolk Place, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A172">Institute of Health Sciences, University of Oulu, University of Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Institute of Health Sciences, University of Oulu, University of Oulu</wicri:regionArea><wicri:noRegion>University of Oulu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A173">Biocenter, University of Oulu, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Biocenter, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Chakravarti, Aravinda" sort="Chakravarti, Aravinda" uniqKey="Chakravarti A" first="Aravinda" last="Chakravarti">Aravinda Chakravarti</name><affiliation wicri:level="2"><nlm:aff id="A17">Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Abecasis, Goncalo R" sort="Abecasis, Goncalo R" uniqKey="Abecasis G" first="Goncalo R" last="Abecasis">Goncalo R. Abecasis</name><affiliation wicri:level="2"><nlm:aff id="A39">Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation wicri:level="1"><nlm:aff id="A15">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A16">University of Iceland, Reykajvik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>University of Iceland, Reykajvik</wicri:regionArea><wicri:noRegion>Reykajvik</wicri:noRegion></affiliation></author><author><name sortKey="Newton Cheh, Christopher" sort="Newton Cheh, Christopher" uniqKey="Newton Cheh C" first="Christopher" last="Newton-Cheh">Christopher Newton-Cheh</name><affiliation wicri:level="2"><nlm:aff id="A35">Center for Human Genetic Research, Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Human Genetic Research, Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A91">Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Levy, Daniel" sort="Levy, Daniel" uniqKey="Levy D" first="Daniel" last="Levy">Daniel Levy</name><affiliation wicri:level="2"><nlm:aff id="A9">Framingham Heart Study, Framingham, Massachusetts, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Framingham Heart Study, Framingham, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A65">Center for Population Studies, National Heart Lung, and Blood Institute, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Population Studies, National Heart Lung, and Blood Institute, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A10">National Heart, Lung and Blood Institute, Bethesda, Maryland, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Heart, Lung and Blood Institute, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Munroe, Patricia B" sort="Munroe, Patricia B" uniqKey="Munroe P" first="Patricia B" last="Munroe">Patricia B. Munroe</name><affiliation wicri:level="4"><nlm:aff id="A8">Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M" last="Psaty">Bruce M. Psaty</name><affiliation wicri:level="4"><nlm:aff id="A26">Cardiovascular Health Research Unit, Division of Internal Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, Division of Internal Medicine, Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A136">Department of Epidemiology, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A174">Department of Health Services, University of Washington, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Health Services, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="2"><nlm:aff id="A138">Group Health Research Institute, Group Health Cooperative, Seattle, Washington, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Group Health Research Institute, Group Health Cooperative, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Caulfield, Mark J" sort="Caulfield, Mark J" uniqKey="Caulfield M" first="Mark J" last="Caulfield">Mark J. Caulfield</name><affiliation wicri:level="4"><nlm:aff id="A8">Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region><settlement type="city">Londres</settlement></placeName><orgName type="university">Université de Londres</orgName></affiliation></author><author><name sortKey="Rao, Dabeeru C" sort="Rao, Dabeeru C" uniqKey="Rao D" first="Dabeeru C" last="Rao">Dabeeru C. Rao</name><affiliation wicri:level="4"><nlm:aff id="A6">Division of Biostatistics, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Biostatistics, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">Université Washington de Saint-Louis</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A7">Department of Genetics, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">Université Washington de Saint-Louis</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A175">Department of Psychiatry, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychiatry, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">Université Washington de Saint-Louis</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A176">Department of Mathematics, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Mathematics, Washington University in St. Louis, School of Medicine, Saint Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">Université Washington de Saint-Louis</orgName></affiliation></author><author><name sortKey="Tobin, Martin D" sort="Tobin, Martin D" uniqKey="Tobin M" first="Martin D" last="Tobin">Martin D. Tobin</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Health Sciences, University of Leicester, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Health Sciences, University of Leicester, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A2">Department of Genetics, University of Leicester, Leicester, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Genetics, University of Leicester, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation></author><author><name sortKey="Elliott, Paul" sort="Elliott, Paul" uniqKey="Elliott P" first="Paul" last="Elliott">Paul Elliott</name><affiliation wicri:level="3"><nlm:aff id="A177">MRC-HPA Centre for Environment and Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC-HPA Centre for Environment and Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><affiliation wicri:level="3"><nlm:aff id="A20">Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A178">Centre of Medical Systems Biology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Centre of Medical Systems Biology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation><nlm:aff id="A4">Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA)</nlm:aff></affiliation></author></analytic><series><title level="j">Nature genetics</title><idno type="ISSN">1061-4036</idno><idno type="eISSN">1546-1718</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Numerous genetic loci influence systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Europeans <sup><xref rid="R1" ref-type="bibr">1</xref>-<xref rid="R3" ref-type="bibr">3</xref></sup>. We now report genome-wide association studies of pulse pressure (PP) and mean arterial pressure (MAP). In discovery (N=74,064) and follow-up studies (N=48,607), we identified at genome-wide significance (<italic>P</italic>= 2.7×10<sup>-8</sup> to <italic>P</italic>=2.3×10<sup>-13</sup>) four novel PP loci (at 4q12 near <italic>CHIC2/PDGFRAI</italic>, 7q22.3 near <italic>PIK3CG</italic>, 8q24.12 in <italic>NOV</italic>, 11q24.3 near <italic>ADAMTS-8</italic>), two novel MAP loci (3p21.31 in <italic>MAP4</italic>, 10q25.3 near <italic>ADRB1</italic>) and one locus associated with both traits (2q24.3 near <italic>FIGN</italic>) which has recently been associated with SBP in east Asians. For three of the novel PP signals, the estimated effect for SBP was opposite to that for DBP, in contrast to the majority of common SBP- and DBP-associated variants which show concordant effects on both traits. These findings indicate novel genetic mechanisms underlying blood pressure variation, including pathways that may differentially influence SBP and DBP.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Ehret, G" uniqKey="Ehret G">G Ehret</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Levy, D" uniqKey="Levy D">D Levy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Newton Cheh, C" uniqKey="Newton Cheh C">C Newton-Cheh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lawes, Cm" uniqKey="Lawes C">CM Lawes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rose, G" uniqKey="Rose G">G Rose</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Domanski, Mj" uniqKey="Domanski M">MJ Domanski</name></author></analytic></biblStruct><biblStruct><analytic><author><name 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Stephens</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Autriche</li><li>Canada</li><li>Chili</li><li>Croatie</li><li>Espagne</li><li>Estonie</li><li>Finlande</li><li>France</li><li>Irlande (pays)</li><li>Islande</li><li>Italie</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suisse</li><li>Suède</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Angleterre de l'Est</li><li>Bade-Wurtemberg</li><li>Bavière</li><li>Californie</li><li>Canton de Vaud</li><li>Caroline du Nord</li><li>Catalogne</li><li>District de Columbia</li><li>District de Haute-Bavière</li><li>District de Karlsruhe</li><li>East Middle Sweden</li><li>Finlande occidentale</li><li>Floride</li><li>Grand Londres</li><li>Groningue (province)</li><li>Hollande-Méridionale</li><li>Hollande-Septentrionale</li><li>Maryland</li><li>Massachusetts</li><li>Michigan</li><li>Missouri (État)</li><li>New 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d'Uppsala</li><li>Université d'Édimbourg</li><li>Université de Californie du Sud</li><li>Université de Cambridge</li><li>Université de Floride du Sud</li><li>Université de Glasgow</li><li>Université de Groningue</li><li>Université de Lausanne</li><li>Université de Londres</li><li>Université de Washington</li><li>Université technique de Munich</li></orgName></list><tree><noCountry><name sortKey="O Onnell, Christopher J" sort="O Onnell, Christopher J" uniqKey="O Onnell C" first="Christopher J" last="O Onnell">Christopher J. O Onnell</name></noCountry><country name="Royaume-Uni"><noRegion><name sortKey="Wain, Louise V" sort="Wain, Louise V" uniqKey="Wain L" first="Louise V" last="Wain">Louise V. Wain</name></noRegion><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Inês" last="Barroso">Inês Barroso</name><name sortKey="Barroso, Ines" sort="Barroso, Ines" uniqKey="Barroso I" first="Inês" last="Barroso">Inês Barroso</name><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><name sortKey="Caulfield, Mark J" sort="Caulfield, Mark J" uniqKey="Caulfield M" first="Mark J" last="Caulfield">Mark J. Caulfield</name><name sortKey="Chambers, John C" sort="Chambers, John C" uniqKey="Chambers J" first="John C" last="Chambers">John C. Chambers</name><name sortKey="Chambers, John C" sort="Chambers, John C" uniqKey="Chambers J" first="John C" last="Chambers">John C. Chambers</name><name sortKey="Clarke, Robert" sort="Clarke, Robert" uniqKey="Clarke R" first="Robert" last="Clarke">Robert Clarke</name><name sortKey="Davies, Gail" sort="Davies, Gail" uniqKey="Davies G" first="Gail" last="Davies">Gail Davies</name><name sortKey="Deary, Ian J" sort="Deary, Ian J" uniqKey="Deary I" first="Ian J" last="Deary">Ian J. Deary</name><name sortKey="Deary, Ian J" sort="Deary, Ian J" uniqKey="Deary I" first="Ian J" last="Deary">Ian J. Deary</name><name sortKey="Elliott, Paul" sort="Elliott, Paul" uniqKey="Elliott P" first="Paul" last="Elliott">Paul Elliott</name><name sortKey="Elliott, Paul" sort="Elliott, Paul" uniqKey="Elliott P" first="Paul" last="Elliott">Paul Elliott</name><name sortKey="Farrall, Martin" sort="Farrall, Martin" uniqKey="Farrall M" first="Martin" last="Farrall">Martin Farrall</name><name sortKey="Farrall, Martin" sort="Farrall, Martin" uniqKey="Farrall M" first="Martin" last="Farrall">Martin Farrall</name><name sortKey="Goel, Anuj" sort="Goel, Anuj" uniqKey="Goel A" first="Anuj" last="Goel">Anuj Goel</name><name sortKey="Goel, Anuj" sort="Goel, Anuj" uniqKey="Goel A" first="Anuj" last="Goel">Anuj Goel</name><name sortKey="Hadley, David" sort="Hadley, David" uniqKey="Hadley D" first="David" last="Hadley">David Hadley</name><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><name sortKey="Hopewell, Jemma C" sort="Hopewell, Jemma C" uniqKey="Hopewell J" first="Jemma C" last="Hopewell">Jemma C. Hopewell</name><name sortKey="Jarvelin, Marjo Riitta" sort="Jarvelin, Marjo Riitta" uniqKey="Jarvelin M" first="Marjo-Riitta" last="Jarvelin">Marjo-Riitta Jarvelin</name><name sortKey="Johnson, Toby" sort="Johnson, Toby" uniqKey="Johnson T" first="Toby" last="Johnson">Toby Johnson</name><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name><name sortKey="Kooner, Jaspal S" sort="Kooner, Jaspal S" uniqKey="Kooner J" first="Jaspal S" last="Kooner">Jaspal S. Kooner</name><name sortKey="Kooner, Jaspal S" sort="Kooner, Jaspal S" uniqKey="Kooner J" first="Jaspal S" last="Kooner">Jaspal S. Kooner</name><name sortKey="Li, Xinzhong" sort="Li, Xinzhong" uniqKey="Li X" first="Xinzhong" last="Li">Xinzhong Li</name><name sortKey="Loos, Ruth Jf" sort="Loos, Ruth Jf" uniqKey="Loos R" first="Ruth Jf" last="Loos">Ruth Jf Loos</name><name sortKey="Lopez, Lorna M" sort="Lopez, Lorna M" uniqKey="Lopez L" first="Lorna M" last="Lopez">Lorna M. Lopez</name><name sortKey="Lopez, Lorna M" sort="Lopez, Lorna M" uniqKey="Lopez L" first="Lorna M" last="Lopez">Lorna M. Lopez</name><name sortKey="Luan, Jian N" sort="Luan, Jian N" uniqKey="Luan J" first="Jian N" last="Luan">Jian N Luan</name><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name><name sortKey="Mcardle, Wendy L" sort="Mcardle, Wendy L" uniqKey="Mcardle W" first="Wendy L" last="Mcardle">Wendy L. Mcardle</name><name sortKey="Munroe, Patricia B" sort="Munroe, Patricia B" uniqKey="Munroe P" first="Patricia B" last="Munroe">Patricia B. Munroe</name><name sortKey="Navarro, Pau" sort="Navarro, Pau" uniqKey="Navarro P" first="Pau" last="Navarro">Pau Navarro</name><name sortKey="Nelson, Christopher P" sort="Nelson, Christopher P" uniqKey="Nelson C" first="Christopher P" last="Nelson">Christopher P. Nelson</name><name sortKey="O Eilly, Paul F" sort="O Eilly, Paul F" uniqKey="O Eilly P" first="Paul F" last="O Eilly">Paul F. O Eilly</name><name sortKey="Ongen, Halit" sort="Ongen, Halit" uniqKey="Ongen H" first="Halit" last="Ongen">Halit Ongen</name><name sortKey="Peden, John F" sort="Peden, John F" uniqKey="Peden J" first="John F" last="Peden">John F. Peden</name><name sortKey="Peden, John F" sort="Peden, John F" uniqKey="Peden J" first="John F" last="Peden">John F. Peden</name><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><name sortKey="Samani, Nilesh J" sort="Samani, Nilesh J" uniqKey="Samani N" first="Nilesh J" last="Samani">Nilesh J. Samani</name><name sortKey="Samani, Nilesh J" sort="Samani, Nilesh J" uniqKey="Samani N" first="Nilesh J" last="Samani">Nilesh J. Samani</name><name sortKey="Scott, James" sort="Scott, James" uniqKey="Scott J" first="James" last="Scott">James Scott</name><name sortKey="Shin, So Youn" sort="Shin, So Youn" uniqKey="Shin S" first="So-Youn" last="Shin">So-Youn Shin</name><name sortKey="Shin, So Youn" sort="Shin, So Youn" uniqKey="Shin S" first="So-Youn" last="Shin">So-Youn Shin</name><name sortKey="Soranzo, Nicole" sort="Soranzo, Nicole" uniqKey="Soranzo N" first="Nicole" last="Soranzo">Nicole Soranzo</name><name sortKey="Soranzo, Nicole" sort="Soranzo, Nicole" uniqKey="Soranzo N" first="Nicole" last="Soranzo">Nicole Soranzo</name><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D" last="Spector">Tim D. Spector</name><name sortKey="Starr, John M" sort="Starr, John M" uniqKey="Starr J" first="John M" last="Starr">John M. Starr</name><name sortKey="Starr, John M" sort="Starr, John M" uniqKey="Starr J" first="John M" last="Starr">John M. Starr</name><name sortKey="Stott, David" sort="Stott, David" uniqKey="Stott D" first="David" last="Stott">David Stott</name><name sortKey="Strachan, David P" sort="Strachan, David P" uniqKey="Strachan D" first="David P" last="Strachan">David P. Strachan</name><name sortKey="Tobin, Martin D" sort="Tobin, Martin D" uniqKey="Tobin M" first="Martin D" last="Tobin">Martin D. Tobin</name><name sortKey="Tobin, Martin D" sort="Tobin, Martin D" uniqKey="Tobin M" first="Martin D" last="Tobin">Martin D. Tobin</name><name sortKey="Vitart, Veronique" sort="Vitart, Veronique" uniqKey="Vitart V" first="Veronique" last="Vitart">Veronique Vitart</name><name sortKey="Wain, Louise V" sort="Wain, Louise V" uniqKey="Wain L" first="Louise V" last="Wain">Louise V. Wain</name><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J" last="Wareham">Nicholas J. Wareham</name><name sortKey="Watkins, Hugh" sort="Watkins, Hugh" uniqKey="Watkins H" first="Hugh" last="Watkins">Hugh Watkins</name><name sortKey="Watkins, Hugh" sort="Watkins, Hugh" uniqKey="Watkins H" first="Hugh" last="Watkins">Hugh Watkins</name><name sortKey="Wild, Sarah H" sort="Wild, Sarah H" uniqKey="Wild S" first="Sarah H" last="Wild">Sarah H. Wild</name><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F" last="Wilson">James F. Wilson</name><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F" last="Wright">Alan F. Wright</name><name sortKey="Zhang, Feng" sort="Zhang, Feng" uniqKey="Zhang F" first="Feng" last="Zhang">Feng Zhang</name><name sortKey="Zhang, Weihua" sort="Zhang, Weihua" uniqKey="Zhang W" first="Weihua" last="Zhang">Weihua Zhang</name><name sortKey="Zhang, Weihua" sort="Zhang, Weihua" uniqKey="Zhang W" first="Weihua" last="Zhang">Weihua Zhang</name><name sortKey="Zhao, Jing Hua" sort="Zhao, Jing Hua" uniqKey="Zhao J" first="Jing Hua" last="Zhao">Jing Hua Zhao</name></country><country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="Verwoert, Germaine C" sort="Verwoert, Germaine C" uniqKey="Verwoert G" first="Germaine C" last="Verwoert">Germaine C. Verwoert</name></region><name sortKey=" Hoen, Peter Ac" sort=" Hoen, Peter Ac" uniqKey=" Hoen P" first="Peter Ac" last=" Hoen">Peter Ac Hoen</name><name sortKey=" Hoen, Peter Ac" sort=" Hoen, Peter Ac" uniqKey=" Hoen P" first="Peter Ac" last=" Hoen">Peter Ac Hoen</name><name sortKey="Alizadeh, Behrooz Z" sort="Alizadeh, Behrooz Z" uniqKey="Alizadeh B" first="Behrooz Z" last="Alizadeh">Behrooz Z. Alizadeh</name><name sortKey="Amin, Najaf" sort="Amin, Najaf" uniqKey="Amin N" first="Najaf" last="Amin">Najaf Amin</name><name sortKey="Aulchenko, Yurii" sort="Aulchenko, Yurii" uniqKey="Aulchenko Y" first="Yurii" last="Aulchenko">Yurii Aulchenko</name><name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I" last="Boomsma">Dorret I. Boomsma</name><name sortKey="Breteler, Monique" sort="Breteler, Monique" uniqKey="Breteler M" first="Monique" last="Breteler">Monique Breteler</name><name sortKey="De Geus, Eco Jc" sort="De Geus, Eco Jc" uniqKey="De Geus E" first="Eco Jc" last="De Geus">Eco Jc De Geus</name><name sortKey="Felix, Janine F" sort="Felix, Janine F" uniqKey="Felix J" first="Janine F" last="Felix">Janine F. Felix</name><name sortKey="Fu, Jingyuan" sort="Fu, Jingyuan" uniqKey="Fu J" first="Jingyuan" last="Fu">Jingyuan Fu</name><name sortKey="Fu, Jingyuan" sort="Fu, Jingyuan" uniqKey="Fu J" first="Jingyuan" last="Fu">Jingyuan Fu</name><name sortKey="Henneman, Peter" sort="Henneman, Peter" uniqKey="Henneman P" first="Peter" last="Henneman">Peter Henneman</name><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><name sortKey="Hotteng, Jouke Jan" sort="Hotteng, Jouke Jan" uniqKey="Hotteng J" first="Jouke-Jan" last="Hotteng">Jouke-Jan Hotteng</name><name sortKey="Janssens, A Cecile Jw" sort="Janssens, A Cecile Jw" uniqKey="Janssens A" first="A Cecile Jw" last="Janssens">A Cecile Jw Janssens</name><name sortKey="Jukema, J Wouter" sort="Jukema, J Wouter" uniqKey="Jukema J" first="J Wouter" last="Jukema">J Wouter Jukema</name><name sortKey="Jukema, J Wouter" sort="Jukema, J Wouter" uniqKey="Jukema J" first="J Wouter" last="Jukema">J Wouter Jukema</name><name sortKey="Jukema, J Wouter" sort="Jukema, J Wouter" uniqKey="Jukema J" first="J Wouter" last="Jukema">J Wouter Jukema</name><name sortKey="Kundu, Suman" sort="Kundu, Suman" uniqKey="Kundu S" first="Suman" last="Kundu">Suman Kundu</name><name sortKey="Lindeman, Jan H" sort="Lindeman, Jan H" uniqKey="Lindeman J" first="Jan H" last="Lindeman">Jan H. Lindeman</name><name sortKey="Lu, Xiaowen" sort="Lu, Xiaowen" uniqKey="Lu X" first="Xiaowen" last="Lu">Xiaowen Lu</name><name sortKey="Mattace Raso, Francesco Us" sort="Mattace Raso, Francesco Us" uniqKey="Mattace Raso F" first="Francesco Us" last="Mattace-Raso">Francesco Us Mattace-Raso</name><name sortKey="Mattace Raso, Francesco Us" sort="Mattace Raso, Francesco Us" uniqKey="Mattace Raso F" first="Francesco Us" last="Mattace-Raso">Francesco Us Mattace-Raso</name><name sortKey="Nolte, Ilja M" sort="Nolte, Ilja M" uniqKey="Nolte I" first="Ilja M" last="Nolte">Ilja M. Nolte</name><name sortKey="Oostra, Ben A" sort="Oostra, Ben A" uniqKey="Oostra B" first="Ben A" last="Oostra">Ben A. Oostra</name><name sortKey="Penninx, Brenda W" sort="Penninx, Brenda W" uniqKey="Penninx B" first="Brenda W" last="Penninx">Brenda W. Penninx</name><name sortKey="Penninx, Brenda W" sort="Penninx, Brenda W" uniqKey="Penninx B" first="Brenda W" last="Penninx">Brenda W. Penninx</name><name sortKey="Penninx, Brenda W" sort="Penninx, Brenda W" uniqKey="Penninx B" first="Brenda W" last="Penninx">Brenda W. Penninx</name><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><name sortKey="Sijbrands, Eric Jg" sort="Sijbrands, Eric Jg" uniqKey="Sijbrands E" first="Eric Jg" last="Sijbrands">Eric Jg Sijbrands</name><name sortKey="Sijbrands, Eric Jg" sort="Sijbrands, Eric Jg" uniqKey="Sijbrands E" first="Eric Jg" last="Sijbrands">Eric Jg Sijbrands</name><name sortKey="Snieder, Harold" sort="Snieder, Harold" uniqKey="Snieder H" first="Harold" last="Snieder">Harold Snieder</name><name sortKey="Stolk, Ronald P" sort="Stolk, Ronald P" uniqKey="Stolk R" first="Ronald P" last="Stolk">Ronald P. Stolk</name><name sortKey="Trompet, Stella" sort="Trompet, Stella" uniqKey="Trompet S" first="Stella" last="Trompet">Stella Trompet</name><name sortKey="Trompet, Stella" sort="Trompet, Stella" uniqKey="Trompet S" first="Stella" last="Trompet">Stella Trompet</name><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="Andre G" last="Uitterlinden">Andre G. Uitterlinden</name><name sortKey="Van Der Klauw, Melanie M" sort="Van Der Klauw, Melanie M" uniqKey="Van Der Klauw M" first="Melanie M" last="Van Der Klauw">Melanie M. Van Der Klauw</name><name sortKey="Van Dijk, Ko Willems" sort="Van Dijk, Ko Willems" uniqKey="Van Dijk K" first="Ko Willems" last="Van Dijk">Ko Willems Van Dijk</name><name sortKey="Van Dijk, Ko Willems" sort="Van Dijk, Ko Willems" uniqKey="Van Dijk K" first="Ko Willems" last="Van Dijk">Ko Willems Van Dijk</name><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><name sortKey="Willemsen, Gonneke" sort="Willemsen, Gonneke" uniqKey="Willemsen G" first="Gonneke" last="Willemsen">Gonneke Willemsen</name><name sortKey="Witteman, Jacqueline Cm" sort="Witteman, Jacqueline Cm" uniqKey="Witteman J" first="Jacqueline Cm" last="Witteman">Jacqueline Cm Witteman</name></country><country name="États-Unis"><region name="Missouri (État)"><name sortKey="Shi, Gang" sort="Shi, Gang" uniqKey="Shi G" first="Gang" last="Shi">Gang Shi</name></region><name sortKey="Abecasis, Goncalo R" sort="Abecasis, Goncalo R" uniqKey="Abecasis G" first="Goncalo R" last="Abecasis">Goncalo R. Abecasis</name><name sortKey="Altshuler, David" sort="Altshuler, David" uniqKey="Altshuler D" first="David" last="Altshuler">David Altshuler</name><name sortKey="Altshuler, David" sort="Altshuler, David" uniqKey="Altshuler D" first="David" last="Altshuler">David Altshuler</name><name sortKey="Altshuler, David" sort="Altshuler, David" uniqKey="Altshuler D" first="David" last="Altshuler">David Altshuler</name><name sortKey="Altshuler, David" sort="Altshuler, David" uniqKey="Altshuler D" first="David" last="Altshuler">David Altshuler</name><name sortKey="Arora, Pankaj" sort="Arora, Pankaj" uniqKey="Arora P" first="Pankaj" last="Arora">Pankaj Arora</name><name sortKey="Bergman, Richard N" sort="Bergman, Richard N" uniqKey="Bergman R" first="Richard N" last="Bergman">Richard N. Bergman</name><name sortKey="Bis, Joshua C" sort="Bis, Joshua C" uniqKey="Bis J" first="Joshua C" last="Bis">Joshua C. Bis</name><name sortKey="Boehnke, Michael" sort="Boehnke, Michael" uniqKey="Boehnke M" first="Michael" last="Boehnke">Michael Boehnke</name><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><name sortKey="Bragg Gresham, Jennifer L" sort="Bragg Gresham, Jennifer L" uniqKey="Bragg Gresham J" first="Jennifer L" last="Bragg-Gresham">Jennifer L. Bragg-Gresham</name><name sortKey="Burke, Gregory L" sort="Burke, Gregory L" uniqKey="Burke G" first="Gregory L" last="Burke">Gregory L. Burke</name><name sortKey="Chakravarti, Aravinda" sort="Chakravarti, Aravinda" uniqKey="Chakravarti A" first="Aravinda" last="Chakravarti">Aravinda Chakravarti</name><name sortKey="Chasman, Daniel I" sort="Chasman, Daniel I" uniqKey="Chasman D" first="Daniel I" last="Chasman">Daniel I. Chasman</name><name sortKey="Chasman, Daniel I" sort="Chasman, Daniel I" uniqKey="Chasman D" first="Daniel I" last="Chasman">Daniel I. Chasman</name><name sortKey="Chen, Yii Der Ida" sort="Chen, Yii Der Ida" uniqKey="Chen Y" first="Yii-Der Ida" last="Chen">Yii-Der Ida Chen</name><name sortKey="Collins, Francis S" sort="Collins, Francis S" uniqKey="Collins F" first="Francis S" last="Collins">Francis S. Collins</name><name sortKey="Debette, Stephanie" sort="Debette, Stephanie" uniqKey="Debette S" first="Stéphanie" last="Debette">Stéphanie Debette</name><name sortKey="Destefano, Anita L" sort="Destefano, Anita L" uniqKey="Destefano A" first="Anita L" last="Destefano">Anita L. Destefano</name><name sortKey="Ehret, Georg B" sort="Ehret, Georg B" uniqKey="Ehret G" first="Georg B" last="Ehret">Georg B. Ehret</name><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name><name sortKey="Fornage, Myriam" sort="Fornage, Myriam" uniqKey="Fornage M" first="Myriam" last="Fornage">Myriam Fornage</name><name sortKey="Ganesh, Santhi K" sort="Ganesh, Santhi K" uniqKey="Ganesh S" first="Santhi K" last="Ganesh">Santhi K. Ganesh</name><name sortKey="Glazer, Nicole L" sort="Glazer, Nicole L" uniqKey="Glazer N" first="Nicole L" last="Glazer">Nicole L. Glazer</name><name sortKey="Guo, Xiuqing" sort="Guo, Xiuqing" uniqKey="Guo X" first="Xiuqing" last="Guo">Xiuqing Guo</name><name sortKey="Hadley, David" sort="Hadley, David" uniqKey="Hadley D" first="David" last="Hadley">David Hadley</name><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B" last="Harris">Tamara B. Harris</name><name sortKey="Hernandez, Dena" sort="Hernandez, Dena" uniqKey="Hernandez D" first="Dena" last="Hernandez">Dena Hernandez</name><name sortKey="Hwang, Shih Jen" sort="Hwang, Shih Jen" uniqKey="Hwang S" first="Shih-Jen" last="Hwang">Shih-Jen Hwang</name><name sortKey="Hwang, Shih Jen" sort="Hwang, Shih Jen" uniqKey="Hwang S" first="Shih-Jen" last="Hwang">Shih-Jen Hwang</name><name sortKey="Hwang, Shih Jen" sort="Hwang, Shih Jen" uniqKey="Hwang S" first="Shih-Jen" last="Hwang">Shih-Jen Hwang</name><name sortKey="Jackson, Anne U" sort="Jackson, Anne U" uniqKey="Jackson A" first="Anne U" last="Jackson">Anne U. Jackson</name><name sortKey="Johnson, Andrew D" sort="Johnson, Andrew D" uniqKey="Johnson A" first="Andrew D" last="Johnson">Andrew D. Johnson</name><name sortKey="Johnson, Andrew D" sort="Johnson, Andrew D" uniqKey="Johnson A" first="Andrew D" last="Johnson">Andrew D. Johnson</name><name sortKey="Larson, Martin G" sort="Larson, Martin G" uniqKey="Larson M" first="Martin G" last="Larson">Martin G. Larson</name><name sortKey="Larson, Martin G" sort="Larson, Martin G" uniqKey="Larson M" first="Martin G" last="Larson">Martin G. Larson</name><name sortKey="Launer, Lenore" sort="Launer, Lenore" uniqKey="Launer L" first="Lenore" last="Launer">Lenore Launer</name><name sortKey="Levy, Daniel" sort="Levy, Daniel" uniqKey="Levy D" first="Daniel" last="Levy">Daniel Levy</name><name sortKey="Levy, Daniel" sort="Levy, Daniel" uniqKey="Levy D" first="Daniel" last="Levy">Daniel Levy</name><name sortKey="Levy, Daniel" sort="Levy, Daniel" uniqKey="Levy D" first="Daniel" last="Levy">Daniel Levy</name><name sortKey="Milaneschi, Yuri" sort="Milaneschi, Yuri" uniqKey="Milaneschi Y" first="Yuri" last="Milaneschi">Yuri Milaneschi</name><name sortKey="Mitchell, Gary F" sort="Mitchell, Gary F" uniqKey="Mitchell G" first="Gary F" last="Mitchell">Gary F. Mitchell</name><name sortKey="Mooser, Vincent" sort="Mooser, Vincent" uniqKey="Mooser V" first="Vincent" last="Mooser">Vincent Mooser</name><name sortKey="Morrison, Alanna C" sort="Morrison, Alanna C" uniqKey="Morrison A" first="Alanna C" last="Morrison">Alanna C. Morrison</name><name sortKey="Najjar, Samer S" sort="Najjar, Samer S" uniqKey="Najjar S" first="Samer S" last="Najjar">Samer S. Najjar</name><name sortKey="Najjar, Samer S" sort="Najjar, Samer S" uniqKey="Najjar S" first="Samer S" last="Najjar">Samer S. Najjar</name><name sortKey="Newton Cheh, Christopher" sort="Newton Cheh, Christopher" uniqKey="Newton Cheh C" first="Christopher" last="Newton-Cheh">Christopher Newton-Cheh</name><name sortKey="Newton Cheh, Christopher" sort="Newton Cheh, Christopher" uniqKey="Newton Cheh C" first="Christopher" last="Newton-Cheh">Christopher Newton-Cheh</name><name sortKey="Palmas, Walter" sort="Palmas, Walter" uniqKey="Palmas W" first="Walter" last="Palmas">Walter Palmas</name><name sortKey="Parker, Alex N" sort="Parker, Alex N" uniqKey="Parker A" first="Alex N" last="Parker">Alex N. Parker</name><name sortKey="Pihur, Vasyl" sort="Pihur, Vasyl" uniqKey="Pihur V" first="Vasyl" last="Pihur">Vasyl Pihur</name><name sortKey="Plump, Andrew" sort="Plump, Andrew" uniqKey="Plump A" first="Andrew" last="Plump">Andrew Plump</name><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M" last="Psaty">Bruce M. 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Rice</name><name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M" last="Ridker">Paul M. Ridker</name><name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M" last="Ridker">Paul M. Ridker</name><name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M" last="Ridker">Paul M. Ridker</name><name sortKey="Rose, Lynda M" sort="Rose, Lynda M" uniqKey="Rose L" first="Lynda M" last="Rose">Lynda M. Rose</name><name sortKey="Shi, Gang" sort="Shi, Gang" uniqKey="Shi G" first="Gang" last="Shi">Gang Shi</name><name sortKey="Singleton, Andrew" sort="Singleton, Andrew" uniqKey="Singleton A" first="Andrew" last="Singleton">Andrew Singleton</name><name sortKey="Siscovick, David" sort="Siscovick, David" uniqKey="Siscovick D" first="David" last="Siscovick">David Siscovick</name><name sortKey="Siscovick, David" sort="Siscovick, David" uniqKey="Siscovick D" first="David" last="Siscovick">David Siscovick</name><name sortKey="Siscovick, David" sort="Siscovick, David" uniqKey="Siscovick D" first="David" last="Siscovick">David Siscovick</name><name sortKey="Smith, Nicholas L" sort="Smith, Nicholas L" uniqKey="Smith N" first="Nicholas L" last="Smith">Nicholas L. Smith</name><name sortKey="Smith, Nicholas L" sort="Smith, Nicholas L" uniqKey="Smith N" first="Nicholas L" last="Smith">Nicholas L. Smith</name><name sortKey="Smith, Nicholas L" sort="Smith, Nicholas L" uniqKey="Smith N" first="Nicholas L" last="Smith">Nicholas L. Smith</name><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name><name sortKey="Taylor, Kent D" sort="Taylor, Kent D" uniqKey="Taylor K" first="Kent D" last="Taylor">Kent D. Taylor</name><name sortKey="Vasan, Ramachandran S" sort="Vasan, Ramachandran S" uniqKey="Vasan R" first="Ramachandran S" last="Vasan">Ramachandran S. Vasan</name><name sortKey="Vasan, Ramachandran S" sort="Vasan, Ramachandran S" uniqKey="Vasan R" first="Ramachandran S" last="Vasan">Ramachandran S. Vasan</name><name sortKey="Voight, Benjamin F" sort="Voight, Benjamin F" uniqKey="Voight B" first="Benjamin F" last="Voight">Benjamin F. Voight</name><name sortKey="Wang, Thomas J" sort="Wang, Thomas J" uniqKey="Wang T" first="Thomas J" last="Wang">Thomas J. Wang</name><name sortKey="Wang, Thomas J" sort="Wang, Thomas J" uniqKey="Wang T" first="Thomas J" last="Wang">Thomas J. Wang</name></country><country name="Suisse"><region name="Canton de Vaud"><name sortKey="Bochud, Murielle" sort="Bochud, Murielle" uniqKey="Bochud M" first="Murielle" last="Bochud">Murielle Bochud</name></region><name sortKey="Beckmann, Jacques S" sort="Beckmann, Jacques S" uniqKey="Beckmann J" first="Jacques S" last="Beckmann">Jacques S. Beckmann</name><name sortKey="Beckmann, Jacques S" sort="Beckmann, Jacques S" uniqKey="Beckmann J" first="Jacques S" last="Beckmann">Jacques S. 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Hercberg</name><name sortKey="Hercberg, Serge" sort="Hercberg, Serge" uniqKey="Hercberg S" first="Serge" last="Hercberg">Serge Hercberg</name><name sortKey="Hercberg, Serge" sort="Hercberg, Serge" uniqKey="Hercberg S" first="Serge" last="Hercberg">Serge Hercberg</name><name sortKey="Lathrop, Mark" sort="Lathrop, Mark" uniqKey="Lathrop M" first="Mark" last="Lathrop">Mark Lathrop</name><name sortKey="Meneton, Pierre" sort="Meneton, Pierre" uniqKey="Meneton P" first="Pierre" last="Meneton">Pierre Meneton</name></country><country name="Italie"><noRegion><name sortKey="Pistis, Giorgio" sort="Pistis, Giorgio" uniqKey="Pistis G" first="Giorgio" last="Pistis">Giorgio Pistis</name></noRegion><name sortKey="Bandinelli, Stefania" sort="Bandinelli, Stefania" uniqKey="Bandinelli S" first="Stefania" last="Bandinelli">Stefania Bandinelli</name><name sortKey="Corre, Tanguy" sort="Corre, Tanguy" uniqKey="Corre T" first="Tanguy" last="Corre">Tanguy Corre</name><name sortKey="Corsi, Anna Maria" sort="Corsi, Anna Maria" uniqKey="Corsi A" first="Anna Maria" last="Corsi">Anna Maria Corsi</name><name sortKey="D Damo, Adamo Pio" sort="D Damo, Adamo Pio" uniqKey="D Damo A" first="Adamo Pio" last="D Damo">Adamo Pio D Damo</name><name sortKey="Fabretto, Antonella" sort="Fabretto, Antonella" uniqKey="Fabretto A" first="Antonella" last="Fabretto">Antonella Fabretto</name><name sortKey="Faletra, Flavio" sort="Faletra, Flavio" uniqKey="Faletra F" first="Flavio" last="Faletra">Flavio Faletra</name><name sortKey="Gasparini, Paolo" sort="Gasparini, Paolo" uniqKey="Gasparini P" first="Paolo" last="Gasparini">Paolo Gasparini</name><name sortKey="Gasparini, Paolo" sort="Gasparini, Paolo" uniqKey="Gasparini P" first="Paolo" last="Gasparini">Paolo Gasparini</name><name sortKey="Masciullo, Corrado" sort="Masciullo, Corrado" uniqKey="Masciullo C" first="Corrado" last="Masciullo">Corrado Masciullo</name><name sortKey="Orru, Marco" sort="Orru, Marco" uniqKey="Orru M" first="Marco" last="Orru">Marco 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sort="Webster, Rebecca J" uniqKey="Webster R" first="Rebecca J" last="Webster">Rebecca J. Webster</name></noRegion><name sortKey="Beilby, John P" sort="Beilby, John P" uniqKey="Beilby J" first="John P" last="Beilby">John P. Beilby</name><name sortKey="Beilby, John P" sort="Beilby, John P" uniqKey="Beilby J" first="John P" last="Beilby">John P. Beilby</name><name sortKey="Beilby, John P" sort="Beilby, John P" uniqKey="Beilby J" first="John P" last="Beilby">John P. Beilby</name><name sortKey="Hung, Joseph" sort="Hung, Joseph" uniqKey="Hung J" first="Joseph" last="Hung">Joseph Hung</name><name sortKey="Hung, Joseph" sort="Hung, Joseph" uniqKey="Hung J" first="Joseph" last="Hung">Joseph Hung</name><name sortKey="Musk, A William" sort="Musk, A William" uniqKey="Musk A" first="A William" last="Musk">A William Musk</name><name sortKey="Musk, A William" sort="Musk, A William" uniqKey="Musk A" first="A William" last="Musk">A William Musk</name><name sortKey="Musk, A William" sort="Musk, A William" uniqKey="Musk A" first="A William" last="Musk">A William Musk</name><name sortKey="Palmer, Lyle J" sort="Palmer, Lyle J" uniqKey="Palmer L" first="Lyle J" last="Palmer">Lyle J. Palmer</name><name sortKey="Palmer, Lyle J" sort="Palmer, Lyle J" uniqKey="Palmer L" first="Lyle J" last="Palmer">Lyle J. Palmer</name></country><country name="Autriche"><noRegion><name sortKey="Schmidt, Helena" sort="Schmidt, Helena" uniqKey="Schmidt H" first="Helena" last="Schmidt">Helena Schmidt</name></noRegion><name sortKey="Gider, Pierre" sort="Gider, Pierre" uniqKey="Gider P" first="Pierre" last="Gider">Pierre Gider</name><name sortKey="Loitfelder, Marisa" sort="Loitfelder, Marisa" uniqKey="Loitfelder M" first="Marisa" last="Loitfelder">Marisa Loitfelder</name><name sortKey="Schmidt, Reinhold" sort="Schmidt, Reinhold" uniqKey="Schmidt R" first="Reinhold" last="Schmidt">Reinhold Schmidt</name><name sortKey="Zeginigg, Marion" sort="Zeginigg, Marion" uniqKey="Zeginigg M" first="Marion" last="Zeginigg">Marion Zeginigg</name></country><country name="Suède"><region name="Svealand"><name sortKey="Igl, Wilmar" sort="Igl, Wilmar" uniqKey="Igl W" first="Wilmar" last="Igl">Wilmar Igl</name></region><name sortKey="Groop, Leif" sort="Groop, Leif" uniqKey="Groop L" first="Leif" last="Groop">Leif Groop</name><name sortKey="Gyllensten, Ulf B" sort="Gyllensten, Ulf B" uniqKey="Gyllensten U" first="Ulf B" last="Gyllensten">Ulf B. Gyllensten</name><name sortKey="Hamsten, Anders" sort="Hamsten, Anders" uniqKey="Hamsten A" first="Anders" last="Hamsten">Anders Hamsten</name><name sortKey="Melander, Olle" sort="Melander, Olle" uniqKey="Melander O" first="Olle" last="Melander">Olle Melander</name></country><country name="Finlande"><noRegion><name sortKey="Lehtim Ki, Terho" sort="Lehtim Ki, Terho" uniqKey="Lehtim Ki T" first="Terho" last="Lehtim Ki">Terho Lehtim Ki</name></noRegion><name sortKey="Jarvelin, Marjo Riitta" sort="Jarvelin, Marjo Riitta" uniqKey="Jarvelin M" first="Marjo-Riitta" last="Jarvelin">Marjo-Riitta Jarvelin</name><name sortKey="Jarvelin, Marjo Riitta" sort="Jarvelin, Marjo Riitta" uniqKey="Jarvelin M" first="Marjo-Riitta" last="Jarvelin">Marjo-Riitta Jarvelin</name><name sortKey="K Honen, Mika" sort="K Honen, Mika" uniqKey="K Honen M" first="Mika" last="K Hönen">Mika K Hönen</name><name sortKey="Laitinen, Jaana" sort="Laitinen, Jaana" uniqKey="Laitinen J" first="Jaana" last="Laitinen">Jaana Laitinen</name><name sortKey="Pouta, Anneli" sort="Pouta, Anneli" uniqKey="Pouta A" first="Anneli" last="Pouta">Anneli Pouta</name><name sortKey="Raitakari, Olli T" sort="Raitakari, Olli T" uniqKey="Raitakari O" first="Olli T" last="Raitakari">Olli T. Raitakari</name><name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M" last="Ridker">Paul M. Ridker</name><name sortKey="Salomaa, Veikko" sort="Salomaa, Veikko" uniqKey="Salomaa V" first="Veikko" last="Salomaa">Veikko Salomaa</name><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name><name sortKey="Tuomilehto, Jaakko" sort="Tuomilehto, Jaakko" uniqKey="Tuomilehto J" first="Jaakko" last="Tuomilehto">Jaakko Tuomilehto</name><name sortKey="Viikari, Jorma" sort="Viikari, Jorma" uniqKey="Viikari J" first="Jorma" last="Viikari">Jorma Viikari</name><name sortKey="Zitting, Paavo" sort="Zitting, Paavo" uniqKey="Zitting P" first="Paavo" last="Zitting">Paavo Zitting</name></country><country name="Croatie"><noRegion><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polašek">Ozren Polašek</name></noRegion><name sortKey="Boban, Mladen" sort="Boban, Mladen" uniqKey="Boban M" first="Mladen" last="Boban">Mladen Boban</name><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name></country><country name="Chili"><noRegion><name sortKey="Eyheramendy, Susana" sort="Eyheramendy, Susana" uniqKey="Eyheramendy S" first="Susana" last="Eyheramendy">Susana Eyheramendy</name></noRegion></country><country name="Irlande (pays)"><noRegion><name sortKey="Buckley, Brendan" sort="Buckley, Brendan" uniqKey="Buckley B" first="Brendan" last="Buckley">Brendan Buckley</name></noRegion></country><country name="Canada"><noRegion><name sortKey="Palmer, Lyle J" sort="Palmer, Lyle J" uniqKey="Palmer L" first="Lyle J" last="Palmer">Lyle J. Palmer</name></noRegion><name sortKey="Palmer, Lyle J" sort="Palmer, Lyle J" uniqKey="Palmer L" first="Lyle J" last="Palmer">Lyle J. Palmer</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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